Evolving EMRSA-15 epidemic in Singapore hospitals

被引：41
作者：
Hsu, Li-Yang
Loomba-Chlebicka, Nichi
Koh, Yin-Ling
Tan, Thean-Yen
Krishnan, Prabha
Lin, Raymond Tzer-Pin
Tee, Nancy Wen-Sin
Fisher, Dale Andrew
Koh, Tse-Hsien
机构：
[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore 119074, Singapore
[2] Singapore Gen Hosp, Singapore 0316, Singapore
[3] Changi Gen Hosp, Singapore, Singapore
[4] Tan Tock Seng Hosp, Singapore, Singapore
[5] Natl Univ Singapore Hosp, Singapore 117548, Singapore
[6] Kandang Kerbau Womens & Childrens Hosp, Singapore, Singapore
来源：
JOURNAL OF MEDICAL MICROBIOLOGY | 2007年 / 56卷 / 03期
关键词：
D O I：
10.1099/jmm.0.46950-0
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The aim of this study was to determine the extent of EMRSA-15 spread in hospitals in Singapore. Molecular analysis of 197 non-duplicate meticillin-resistant Staphylococcus aureus (MRSA) isolates collected from five acute care public hospitals in Singapore in May 2005 revealed that 66 (33.5%) were EMRSA-15 while 121 (61.4%) belonged to the endemic multidrug-resistant ST239 clone. Median and mode vancomycin MIC; for both major clones of health-care-associated MRSA were relatively high at 2.0 mu g ml(-1). Subsequent laboratory surveillance data collected from the first half of 2006 confirmed increasing numbers of the EMRSA-15 clone - ranging from 25.0 to 66.1% of all MRSA isolated in local hospitals-replacing the ST239 clone island-wide.
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收藏
页码：376 / 379
页数：4
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