Inflammatory bowel disease and pregnancy: an update

被引:11
作者
Kwan, Lola Y. [2 ]
Mahadevan, Uma [1 ]
机构
[1] Univ Calif San Francisco, San Francisco, CA 94115 USA
[2] Univ Rochester, Med Ctr, Rochester, NY 14642 USA
关键词
adalimumab; certolizumab; Crohn's disease; inflammatory bowel disease; infliximab; pregnancy; ulcerative colitis; POUCH-ANAL ANASTOMOSIS; REFRACTORY ULCERATIVE-COLITIS; CROHNS-DISEASE; CONGENITAL-ABNORMALITIES; CYCLOSPORINE TREATMENT; 5-AMINOSALICYLIC ACID; LIVER-TRANSPLANTATION; RESTORATIVE PROCTOCOLECTOMY; GESTATIONAL EXPOSURE; MAINTENANCE THERAPY;
D O I
10.1586/ECI.10.35
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Women with inflammatory bowel disease have similar rates of conception to the general population unless they have had pelvic surgery. Once pregnant, regardless of disease activity, they have an increased risk of adverse pregnancy outcome and should be followed as high-risk obstetric patients. Most medications are compatible with pregnancy and lactation, as described in this article. Ideally, women should discuss their plans for pregnancy with their physician prior to conception so that risks and benefits can be reviewed, medications adjusted and healthcare maintenance updated. Once pregnant, a multidisciplinary team of gastroenterologists, obstetricians and pediatricians should help to ensure the best care for the mother and child.
引用
收藏
页码:643 / 657
页数:15
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