Visceral sensory inputs to the endocrine hypothalamus

被引:71
作者
Rinaman, Linda [1 ]
机构
[1] Univ Pittsburgh, Dept Neurosci, Pittsburgh, PA 15260 USA
关键词
vagus; spinal; nucleus of the solitary tract; ventrolateral medulla; parabrachial nucleus; paraventricular nucleus of the hypothalamus; supraoptic nucleus of the hypothalamus; postnatal development; glucagon-like peptide 1; corticotropin releasing hormone; oxytocin; vasopressin;
D O I
10.1016/j.yfrne.2007.02.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Interoceptive feedback signals from the body are transmitted to hypothalamic neurons that control pituitary hormone release. This review article describes the organization of central neural pathways that convey ascending visceral sensory signals to endocrine neurons in the paraventricular (PVN) and supraoptic nuclei (SON) of the hypothalamus in rats. A special emphasis is placed on viscerosensory inputs to corticotropin releasing factor (CRF)-containing PVN neurons that drive the hypothalamic-pituitary-adrenal axis, and on inputs to magnocellular PVN and SON neurons that release vasopressin (AVP) or oxytocin (OT) from the posterior pituitary. The postnatal development of these ascending pathways also is considered. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:50 / 60
页数:11
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