Experience-dependent rescaling of entorhinal grids

被引：374
作者：
Barry, Caswell
Hayman, Robin
Burgess, Neil
Jeffery, Kathryn J.
机构：
[1] UCL, Inst Cognit Neurosci, London WC1N 3AR, England
[2] UCL, Dept Anat, London WC1E 6BT, England
[3] UCL, Dept Psychol, London WC1H 0AP, England
来源：
NATURE NEUROSCIENCE | 2007年 / 10卷 / 06期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1038/nn1905
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The firing pattern of entorhinal 'grid cells' is thought to provide an intrinsic metric for space. We report a strong experience-dependent environmental influence: the spatial scales of the grids (which are aligned and have fixed relative sizes within each animal) vary parametrically with changes to a familiar environment's size and shape. Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment.
引用
收藏
页码：682 / 684
页数：3
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