The first enantioselective aza-Diels-Alder reactions of imino dienophiles on use of a chiral zirconium catalyst

被引：0

作者：

Kobayashi, S ^{[1
]}

Komiyama, S

Ishitani, H

机构：

[1] Sci Univ Tokyo, Fac Sci, Dept Appl Chem, Tokyo 162, Japan

[2] Japan Sci & Technol Corp, CREST, Shinjuku Ku, Tokyo 162, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1998年 / 37卷 / 07期

关键词：

asymmetric catalysis; cycloadditions; homogeneous catalysis; Lewis acids; zirconium;

D O I：

10.1002/(SICI)1521-3773(19980420)37:7<979::AID-ANIE979>3.0.CO;2-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral dihydropyridone derivatives 3 are obtained in high yields and with good enantioselectivities by the title reaction of aldimines such as 1 with Danishefsky's diene 2. 6,6'-Dibromo-1,1'-binaphthol complexes with Group 4 metals serve as catalysts; zirconium proved to be especially effective.

引用

页码：979 / 981

页数：3

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