COVID-19: Where is the treatment?

被引：2

作者：

Sabeerabi, Bonala ^{[1
]}

Vemula, Sarojamma ^{[2
]}

Vadde, Ramakrishna ^{[3
]}

Nagaraju, Ganji Purnachandra ^{[4
]}

机构：

[1] Biostandups, Dept Biochem, Hyderabad 500039, Telangana, India

[2] Govt Med Coll, Dept Microbiol, Anantapur 515001, Andhra Pradesh, India

[3] Yogi Vemana Univ, Dept Biotechnol & Bioinformat, Kadapa 516003, Andhra Pradesh, India

[4] Emory Univ, Dept Hematol & Med Oncol, 1365 Clifton Rd Winship C 3025, Atlanta, GA 30322 USA

来源：

WORLD JOURNAL OF CLINICAL ONCOLOGY | 2021年 / 12卷 / 05期

关键词：

COVID-19; Meta-analysis; Therapeutics; Anti-viral drugs; Immune therapy; Corticosteroids; CORONAVIRUS; INFECTION; HYDROXYCHLOROQUINE; METAANALYSIS; EFFICACY; THERAPY; SAFETY; IMPACT; RISK; SARS;

D O I：

10.5306/wjco.v12.i5.309

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Even though the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is related to SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), identifying effective and safe therapeutic strategies remains challenging. In search of finding effective treatments to eradicate the virus and improve disease symptoms, scientists are exploring possible therapies such as anti-viral, anti-malaria, immune therapy, and hormone treatments. However, the efficacy of these treatments was not validated on either SARS-CoV or MERS-CoV. In this study, we have reviewed synthetic evidence achieved through systematic and meta-analysis of therapeutics specific for SARS-CoV-2 and observed that the use of the above-mentioned therapies had no clinical benefits in coronavirus disease 2019 patients and, conversely, displayed side effects.

引用

页码：309 / 322

页数：14

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