A novel support for enzyme adsorption: properties and applications of aerogels in low water media

被引：16

作者：

Basso, A

De Martin, L

Ebert, C

Gardossi, L

Tomat, A

Casarci, M

Rosi, OL

机构：

[1] Univ Trieste, Dipartimento Sci Farmaceut, I-34127 Trieste, Italy

[2] CR Casaccia, ENEA, Rome, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)01522-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aerogels, because of their porosity, have a great ability to adsorb water, and this characteristic was exploited to extend the applicability of aerogels for the adsorption and entrapment of hydrolases to be used in organic media. The applicability of aerogels as solid supports for immobilisation of the enzymes PGA, thermolysin and alpha -chymotrypsin was assayed. By controlling the distribution of water between the catalyst, the support and the reaction medium, aerogel preserves the catalytic activity of the enzymes and prevents hydrolytic reactions. (C) 2000 Elsevier Science Ltd, All rights reserved.

引用

页码：8627 / 8630

页数：4

共 10 条

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