Cognition in a multiple system atrophy series of cases from Argentina

被引：7

作者：

Gatto, Emilia ^{[1
,2
]}

Demey, Ignacio ^{[3
]}

Sanguinetti, Ana ^{[1
]}

Parisi, Virginia ^{[2
]}

Etcheverry, Jose Luis ^{[1
]}

Rojas, Galeno ^{[3
]}

Wenning, Gregor K. ^{[2
,4
]}

机构：

[1] Inst Neurociencias Buenos Aires INEBA, Dept Movement Disorders, Buenos Aires, DF, Argentina

[2] Sanatorio Trinidad Mitre, Buenos Aires, DF, Argentina

[3] Inst Neurociencias Buenos Aires INEBA, Unit Cognit Neurosci, Buenos Aires, DF, Argentina

[4] Med Univ Innsbruck, Dept Neurol, Div Neurobiol, A-6020 Innsbruck, Austria

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2014年 / 72卷 / 10期

关键词：

parkinsonism; multiple system atrophy; cognition; CONSENSUS STATEMENT; CEREBELLAR TYPE; PERFORMANCE; DIAGNOSIS; DEFICITS; DISEASE;

D O I：

10.1590/0004-282X20140127

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cognitive dysfunction may occur in 17-40% of patients with multiple system atrophy (MSA). It has been suggested a milder cognitive impairment in cerebellar (MSA-C) than in parkinsonian variant (MSA-P). However, differences in cognitive profiles remain under discussion. Objective: To evaluate cognitive features in a series of patients with "probable MSA" from Argentina. Method: After informed consent was obtained, an extensive cognitive tests battery was administered. Nine patients (6 MSA-P and 3 MSA-C) composed the sample. Results: Depression was detected in 43% of patients. Seven patients showed at least one cognitive domain impairment. Temporospatial orientation, visuospatial abilities, executive and attentional functions, episodic memory and language were compromised in MSA-P, while MSA-C dysfunction was restricted to attentional and executive domains. Conclusion: Despite the small sample size, our findings could suggest a more widespread cognitive impairment in MSA-P than MSA-C.

引用

页码：773 / 776

页数：4

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