Obesity increases the risk of incident asthma among adults

被引：173

作者：

Rönmark, E

Andersson, C

Nyström, L

Forsberg, B

Järvholm, B

Lundbäck, B

机构：

[1] Sunderby Cent Hosp Norrbotten, Dept Med, Obstruct Lung Dis No Sweden Studies, Lulea, Sweden

[2] Karolinska Inst, Natl Inst Environm Med, Lung & Allergy Res, Stockholm, Sweden

[3] Umea Univ, Dept Publ Hlth & Clin Med, Div Resp Med & Allergy, Umea, Sweden

[4] Umea Univ, Dept Epidemiol, Umea, Sweden

[5] Umea Univ, Div Occupat & Environm Med, Umea, Sweden

[6] Umea Univ, Dept Environm Hlth Sci, Umea, Sweden

来源：

EUROPEAN RESPIRATORY JOURNAL | 2005年 / 25卷 / 02期

关键词：

adults; epidemiology; incident asthma; obesity;

D O I：

10.1183/09031936.05.00054304

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The annual incidence of asthma in adults in northern Sweden has been estimated at 2.3 per thousand population. Risk factors for incident asthma among adults were studied in a case-referent study based on incident cases of asthma during 1995-1999. The healthcare providers reported suspected cases of incident asthma. After clinical examination, 309 (65% female) of 473 reported subjects were included. Inclusion criteria were a history of incident asthma (onset <12 months) and verified bronchial variability. Referents were randomly selected and stratified by age, sex and area of residence. The significant risk factors were hay fever, a family history of asthma, ex-smoking status and elevated body mass index (25.0-29.9 and greater than or equal to30). The risk factor pattern was similar for females and males, and increased body mass index was a significant risk factor for both males and females, as well as for allergic and nonallergic subjects. In conclusion, in addition to hay fever, a family history of asthma, allergic sensitisation and ex-smoking status, increased body mass index was a significant risk factor for incident asthma independent of sex and allergic status.

引用

页码：282 / 288

页数：7

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