Toxoplasma gondii, Dirofilaria immitis, feline immunodeficiency virus (FIV), and feline leukemia virus (FeLV) infections in stray and pet cats (Felis catus) in northwest China: co-infections and risk factors

被引：36
作者：
Cong, Wei [1 ,2 ]
Meng, Qing-Feng [3 ]
Blaga, Radu [4 ]
Villena, Isabelle [5 ]
Zhu, Xing-Quan [2 ,6 ]
Qian, Ai-Dong [1 ]
机构：
[1] Jilin Agr Univ, Coll Anim Sci & Technol, Changchun 130118, Jilin Province, Peoples R China
[2] Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol, Lanzhou 730046, Gansu, Peoples R China
[3] Jilin Entry Exit Inspect & Quarantine Bur, Changchun 130118, Jilin Province, Peoples R China
[4] ANSES, Lab Sante Anim, Unite Epidemiol, Maisons Alfort, France
[5] USC Epitoxo, CHU Reims, Toxoplasmose Toxoplasma Biol Resource Ctr BRC, Ctr Natl Reference CNR,Lab Parasitol,EA3800,IFR53, Reims, Anses Lerpaz, France
[6] Yangzhou Univ, Coll Vet Med, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China
来源：
PARASITOLOGY RESEARCH | 2016年 / 115卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Toxoplasma gondii; Dirofilaria immitis; Feline immunodeficiency virus; Feline leukemia virus; Cats; Northwest China; GENETIC-CHARACTERIZATION; SOUTHWESTERN CHINA; SEROLOGICAL SURVEY; DOMESTIC CATS; SEROPREVALENCE; PREVALENCE; EPIDEMIOLOGY; HOUSEHOLD; GENOTYPES; DISEASE;
D O I：
10.1007/s00436-015-4738-y
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
This study was conducted to estimate the prevalence of Toxoplasma gondii, Dirofilaria immitis, feline immunodeficiency virus (FIV), and feline leukemia virus (FeLV) infections among stray and pet cats in Lanzhou, northwest China, and to identify the influence of age, gender, and regions on seropositivity. T. gondii antibodies were examined in cat sera by the modified agglutination test (MAT). The circulating antigens of D. immitis and FeLV and specific antibodies to FIV were examined using kits commercially available. The overall prevalence of T. gondii, FIV, FeLV, and D. immitis was 19.34, 9.12, 11.33, and 3.04 %, respectively. For the genetic characterization of T. gondii genotypes in cats, genomic DNA was extracted from the seropositive cats and the T. gondii B1 gene was amplified using a semi-nested PCR. DNA samples giving positive B1 amplification were then genotyped using multilocus PCR-RFLP. Two T. gondii genotypes (ToxoDB#9 and ToxoDB#1) were identified. Results of the multivariate logistic regression analysis showed that older cats are more likely to be seropositive than juveniles for T. gondii, FIV, FeLV, and D. immitis. This is the first report of T. gondii genotypes in cats in northwest China. Moreover, the present study is the first study of retrovirus and D. immitis seroprevalence in cats in China. The results revealed that T. gondii, FIV, and FeLV infections are common in stray and pet cats in northwest China.
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收藏
页码：217 / 223
页数：7
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