Potential applications of boron nitride nanotubes as drug delivery systems

被引:78
|
作者
Ciofani, Gianni [1 ]
机构
[1] Italian Inst Technol, Scuola Super St Anna, Ctr MicroBioRobot, Smart Mat Lab, I-56025 Pisa, Italy
关键词
biocompatibility; boron neutron capture therapy; boron nitride nanotubes; drug delivery; drug targeting; nanocarriers; nanomedicine; THERAPY; CELLS; DEFORMATION; PROTEINS;
D O I
10.1517/17425247.2010.499897
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In recent years, there has been an explosion of research in the 'bio-nano' field, with the discovery and introduction of ever more fascinating materials for applications as drug delivery systems, sensors, transducers, and so on. The author's group, for the first time in the literature, proposed boron nitride nanotubes as a valid alternative to carbon nanotubes and other kinds of inorganic materials, because of their improved chemical properties that theoretically guarantee better stability and compatibility in a biological context. In this paper, the bio-applications of boron nitride nanotubes that have emerged in the literature are summarized, with special attention given to their exploitation as safe drug delivery and targeting carriers Finally, the possibility of combining their physical and chemical properties is approached, highlighting the features that render these innovative nanovectors unique and exceptional candidates for many bio-applications.
引用
收藏
页码:889 / 893
页数:5
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