Potential applications of boron nitride nanotubes as drug delivery systems

被引:78
|
作者
Ciofani, Gianni [1 ]
机构
[1] Italian Inst Technol, Scuola Super St Anna, Ctr MicroBioRobot, Smart Mat Lab, I-56025 Pisa, Italy
关键词
biocompatibility; boron neutron capture therapy; boron nitride nanotubes; drug delivery; drug targeting; nanocarriers; nanomedicine; THERAPY; CELLS; DEFORMATION; PROTEINS;
D O I
10.1517/17425247.2010.499897
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In recent years, there has been an explosion of research in the 'bio-nano' field, with the discovery and introduction of ever more fascinating materials for applications as drug delivery systems, sensors, transducers, and so on. The author's group, for the first time in the literature, proposed boron nitride nanotubes as a valid alternative to carbon nanotubes and other kinds of inorganic materials, because of their improved chemical properties that theoretically guarantee better stability and compatibility in a biological context. In this paper, the bio-applications of boron nitride nanotubes that have emerged in the literature are summarized, with special attention given to their exploitation as safe drug delivery and targeting carriers Finally, the possibility of combining their physical and chemical properties is approached, highlighting the features that render these innovative nanovectors unique and exceptional candidates for many bio-applications.
引用
收藏
页码:889 / 893
页数:5
相关论文
共 50 条
  • [31] In-Flight Plasma Functionalization of Boron Nitride Nanotubes with Ammonia for Composite Applications
    Iannitto, Robyn
    Shin, Homin
    Rubi, Yadienka Martinez
    Simard, Benoit
    Coulombe, Sylvain
    ACS APPLIED NANO MATERIALS, 2020, 3 (01): : 294 - 302
  • [32] Review On The Application Of Boron Nitride Nanotubes
    Wang, Youjun
    Chen, Hao
    Li, Yanjiao
    PROCEEDINGS OF THE 2016 5TH INTERNATIONAL CONFERENCE ON ENVIRONMENT, MATERIALS, CHEMISTRY AND POWER ELECTRONICS, 2016, 84 : 525 - 529
  • [33] Cytocompatibility, Interactions, and Uptake of Polyethyleneimine-Coated Boron Nitride Nanotubes by Living Cells: Confirmation of Their Potential for Biomedical Applications
    Ciofani, Gianni
    Raffa, Vittoria
    Menciassi, Arianna
    Cuschieri, Alfred
    BIOTECHNOLOGY AND BIOENGINEERING, 2008, 101 (04) : 850 - 858
  • [34] Dendritic systems in drug delivery applications
    Jain, Narendra K.
    Asthana, Abhay
    EXPERT OPINION ON DRUG DELIVERY, 2007, 4 (05) : 495 - 512
  • [35] On the Mechanical Behavior of Boron Nitride Nanotubes
    Ghassemi, H. M.
    Yassar, R. S.
    APPLIED MECHANICS REVIEWS, 2010, 63 (02) : 1 - 7
  • [36] Preparation of Boron Nitride Nanotubes Aqueous Dispersions for Biological Applications
    Ciofani, Gianni
    Raffa, Vittoria
    Menciassi, Arianna
    Dario, Paolo
    JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2008, 8 (12) : 6223 - 6231
  • [37] Nanostructures of boron nitride: A promising nanocarrier for anti-cancer drug delivery
    Jasim, Saade Abdalkareem
    Al-Lami, Mohammed Sabar
    Ameer, A. J.
    Shather, A. H.
    Aldhalmi, Ahmed Khalid
    Taki, Anmar Ghanim
    Ahmed, Batool Ali
    Al-Hamdani, Mais Mazin
    Saraswat, Shelesh Krishna
    MICRO AND NANOSTRUCTURES, 2024, 185
  • [38] Exploring boron nitride nanostructures for effective pyrazinamide drug delivery: A DFT study
    Chou-Yi, Hsu
    Mutar, Ayad Abdulrazzaq
    Ameer, A. J.
    Kadhim, Mustafa M.
    Hamza, Thulfeqar Ahmed
    Alsailawi, H. A.
    Altimari, Usama S.
    Alawadi, Ahmed
    Alsalamy, Ali
    COMPUTATIONAL AND THEORETICAL CHEMISTRY, 2023, 1230
  • [39] Hexagonal boron nitride nanomaterials for biomedical applications
    Wang, Congling
    Long, Yanyang
    Deng, Yuxian
    Han, Yuxin
    Tishkevich, Daria
    Ha, Minh Ngoc
    Weng, Qunhong
    BMEMAT, 2024, 2 (02):
  • [40] In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review
    Kakarla, Akesh Babu
    Kong, Ing
    NANOMATERIALS, 2022, 12 (12)