A newly identified protein from Akkermansia muciniphila stimulates GLP-1 secretion

被引：54
作者：
Cani, Patrice D. [1 ,2 ,3 ]
Knauf, Claude [2 ,3 ,4 ]
机构：
[1] Catholic Univ Louvain, WELBIO Walloon Excellence Life Sci & BIOtechnol, Metab & Nutr Res Grp, UCLouvain,Louvain Drug Res Inst, Brussels, Belgium
[2] Int Res Project IRP, European Lab NeuroMicrobiota, Brussels, Belgium
[3] Int Res Project IRP, European Lab NeuroMicrobiota, Toulouse, France
[4] Univ Paul Sabatier Toulouse III, CHU Purpan, INSERM, U1220,Inst Rech Sante Digest IRSD, Pl Docteur Baylac,CS 60039, F-31024 Toulouse 3, France
来源：
CELL METABOLISM | 2021年 / 33卷 / 06期
关键词：
D O I：
10.1016/j.cmet.2021.05.004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Akkermansia muciniphila is a gut commensal known to improve host metabolism. The outer membrane protein Amuc_1100 has been shown to partially replicate these beneficial effects. Here, Yoon et al. (2021) have identified a novel protein (P9) secreted by A. muciniphila that stimulates GLP-1 secretion, thereby adding new insight to the biomolecule era to treat metabolic diseases.
引用
收藏
页码：1073 / 1075
页数：3
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