D-amino acids in nature, agriculture and biomedicine

被引：78

作者：

Grishin, D. V. ^{[1
]}

Zhdanov, D. D. ^{[1
,2
]}

Pokrovskaya, M. V. ^{[1
]}

Sokolov, N. N. ^{[1
]}

机构：

[1] Inst Biomed Chem, Moscow, Russia

[2] Peoples Friendship Univ Russia, Moscow, Russia

来源：

ALL LIFE | 2020年 / 13卷 / 01期

基金：

俄罗斯科学基金会;

关键词：

L; D-amino acids; peptides; biochemistry; stereoisomerism; biomedicine; agriculture; D-SERINE; PHYSIOLOGICAL FUNCTIONS; ABSORPTION KINETICS; CONTAINING PEPTIDES; PROTEIN DIGESTION; ESCHERICHIA-COLI; TRANSFER-RNAS; D-ASPARTATE; NITROGEN; HOMOCHIRALITY;

D O I：

10.1080/21553769.2019.1622596

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Information accumulated over the past decades on the physiological functions and metabolic pathways of biosynthesis and degradation of D-amino acids has led to a renewed interest in their study. These isomers are known to form both in nature and during the chemical synthesis of L-amino acids for feeding and pharmacological purposes, as well as in the industrial processing of some raw materials. This article discusses the positive and negative effects of D-amino acids on the human body, animals and the environment. In addition, the scientific data concerning the mechanisms of cytotoxic action of D-amino acids and their industrial and biomedical potential are summarized.

引用

页码：11 / 22

页数：12

共 100 条

[1]

[Anonymous], AMINO ACIDS ANIMAL N

[2] D-arginase of Arthrobacter sp KUJ 8602:: Characterization and its identity with Zn2+-guanidinobutyrase [J].