Polymer-supported triacetoxyborohydride: a novel reagent of choice for reductive amination

被引：19

作者：

Bhattacharyya, S ^{[1
]}

Rana, S ^{[1
]}

Gooding, OW ^{[1
]}

Labadie, J ^{[1
]}

机构：

[1] Argonaut Technol, Foster City, CA 94404 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 27期

关键词：

D O I：

10.1016/S0040-4039(03)01167-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel polymer-supported triacetoxyborohydride reagent for reductive amination of aldehydes and ketones is reported. The bound reagent was found to be shelf-stable and provided broad scope and reactivity in reductive amination reactions under mild reaction conditions. Streamlined protocols for its application in reductive amination reactions using both primary and secondary amines are described. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：4957 / 4960

页数：4

共 27 条

[1] Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride. Studies on direct and indirect reductive amination procedures [J].