Angiotensin II type 1 receptor blocker, telmisartan reduces brain ischemic damage via inhibition of AT1 receptor and activation of PPARγ

被引：0
|
作者：
Iwanami, Jun [1 ]
Mogi, Masaki [1 ]
Min, Li-Juan [1 ]
Tsukuda, Kana [1 ]
Sakata, Akiko [1 ]
Fei, Jing [1 ]
Iwai, Masaru [1 ]
Horiuchi, Masatsugu [1 ]
机构：
[1] Ehime Univ, Grad Sch Med, Dept Mol Cardiovasc Biol & Pharmacol, Matsuyama, Ehime 790, Japan
来源：
ENDOCRINE JOURNAL | 2010年 / 57卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：S400 / S400
页数：1
相关论文
共 50 条
  • [1] Angiotensin II type 1 receptor blocker, telmisartan, reduced ischemic brain damage partly due to the activation of peroxisome proliferator-activated receptor γ in diabetes mouse model
    Iwanami, Jun
    Mogi, Masaki
    Li, Jian-Mei
    Min, Li-Juan
    Tsukuda, Kana
    Fujita, Teppei
    Sakata, Akiko
    Iwai, Masaru
    Horiuchi, Masatsugu
    HYPERTENSION, 2008, 52 (04) : E59 - E59
  • [2] Angiotensin II AT1 receptor antagonist telmisartan reduces brain damage after experimental intracerebral hemorrhage in normotensive rats
    Chu, K
    Lee, ST
    Jung, KH
    Kim, SJ
    Sinn, DI
    Park, JH
    Lee, KB
    Kim, M
    Roh, JK
    ANNALS OF NEUROLOGY, 2005, 58 : S9 - S9
  • [3] Effect of Angiotensin II Type 1 receptor blocker, Candesartan, and β1 adrenoceptor blocker, Atenolol, on brain damage in ischemic stroke
    Saad, M. Ahdy A.
    Abbas, Amr M.
    Boshra, V.
    Elkhateeb, M.
    El Aal, I. Abd
    ACTA PHYSIOLOGICA HUNGARICA, 2010, 97 (02) : 159 - 171
  • [4] Angiotensin II Type1 Receptor Blocker, Telmisartan, Decreased Brain Damage Via Peroxisome Proliferator-Activated Receptor Gamma Activation in Diabetes Model Mouse.
    Iwanami, Jun
    Mogi, Masaki
    Li, Jian-Mei
    Min, Li-Juan
    Tsukuda, Kana
    Fujita, Teppei
    Sakata, Akiko
    Iwai, Masaru
    Horiuchi, Masatsugu
    STROKE, 2009, 40 (04) : E211 - E211
  • [5] Downregulation of Angiotensin II type 1 receptor by Telmisartan through PPAR gamma
    Imayama, I
    Fukuyama, K
    Ono, H
    Ohtsubo, H
    Sunagawa, K
    Ichiki, T
    HYPERTENSION, 2005, 46 (04) : 842 - 842
  • [6] Valsartan and Telmisartan Abrogate Angiotensin II-induced Downregulation of ABCA1 Expression Via AT1 Receptor, Rather than AT2 Receptor or PPARγ Activation
    Chen, Hong-Ying
    Xu, Zhen
    Chen, Lian-Feng
    Wang, Wei
    Fang, Quan
    Yan, Xiao-Wei
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2012, 59 (06) : 570 - 575
  • [7] Suppression of Experimental Autoimmune Uveitis by Angiotensin II Type 1 Receptor Blocker Telmisartan
    Okunuki, Yoko
    Usui, Yoshihiko
    Nagai, Norihiro
    Kezuka, Takeshi
    Ishida, Susumu
    Takeuchi, Masaru
    Goto, Hiroshi
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2009, 50 (05) : 2255 - 2261
  • [8] The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice
    Nickel, Laura
    Suenderhauf, Annika
    Rawish, Elias
    Stoelting, Ines
    Derer, Stefanie
    Thorns, Christoph
    Matschl, Urte
    Othman, Alaa
    Sina, Christian
    Raasch, Walter
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [9] The angiotensin type 1 receptor blocker irbesarlan induces adiponectin expression via PPAR-γ activation
    Clasen, R
    Sprang, C
    Schupp, M
    Clemenz, M
    Krikov, M
    Thoene-Reineke, C
    Unger, T
    Kintscher, U
    CIRCULATION, 2004, 110 (17) : 835 - 835
  • [10] Telmisartan, an angiotensin II type 1 receptor blocker, reduces IOP and prevents axon loss in mice with experimental glaucoma
    Hazlewood, Ralph J.
    Kuchtey, John
    Kuchtey, Rachel W.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
12345