Clinical rubella reinfection during pregnancy in a previously vaccinated woman

被引:18
作者
Aboudy, Y [1 ]
Barnea, B
Yosef, L
Frank, T
Mendelson, E
机构
[1] Chaim Sheba Med Ctr, Cent Virol Lab, Natl Rubella Ctr, IL-52621 Tel Hashomer, Israel
[2] Minist Hlth, Publ Hlth Serv, Cent Virol Lab, IL-52621 Tel Hashomer, Israel
关键词
D O I
10.1053/jinf.2000.0716
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We report a documented case of clinically apparent rubella reinfection during pregnancy with rubelliform rash and fever followed by lymphodenopathy at the 18th week of gestation, in a previously vaccinated woman with haemagglutination inhibition (HI) antibody titre of 1:32. The serological tests results (including neutralizing antibodies) demonstrated a significant rise in her rubella specific IgG level with strongly positive IgM reactivity. In addition, rubella-specific IgG antibody avidity testing displayed high avidity index (53-88%) typical of rubella reinfection, Umbilical cord blood, drawn by sonographic-guided cordocentesis at 24 weeks' gestation, was found to be negative for rubella-specific IgM antibody The pregnancy was continued to term, and a healthy infant was born, (C) 2000 The British Infection Society.
引用
收藏
页码:187 / 189
页数:3
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