Further parameters of insight and neuropsychological deficit in schizophrenia and other chronic mental disease

被引:126
作者
Young, DA
Zakzanis, KK
Bailey, C
Davila, R
Griese, J
Sartory, G
Thom, A
机构
[1] Queen St Mental Hlth Ctr, Archway Clin, Toronto, ON M6J 1H4, Canada
[2] York Univ, Dept Psychol, Toronto, ON M3J 2R7, Canada
[3] Baycrest Ctr Geriatr Care, Dept Psychol, Toronto, ON, Canada
[4] Ontario Inst Studies Educ, Toronto, ON M5S 1V6, Canada
[5] Berg Univ Gesamthsch Wuppertal, Dept Psychol, Wuppertal, Germany
关键词
D O I
10.1097/00005053-199801000-00007
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Evidence has begun to accumulate which suggests that lack of awareness of illness in schizophrenia is related to and possibly the result of a cognitive deficit involving prefrontal cerebral dysfunction. This study further explores this relationship along with other domains of self-awareness in chronic schizophrenics and other subjects with serious mental disorders. One hundred eight schizophrenics and 21 bipolar subjects from three separate sites in Britain, Germany, and Canada were administered the Wisconsin Card Sorting Test and three measures of self-awareness. Lack of illness awareness and other domains of self-knowledge were significantly more related to poorer neuropsychological performance in schizophrenia patients than in the other subjects. The results support the hypothesis that lack of illness awareness is related to defective frontal lobe functioning as indexed by neuropsychological measures.
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页码:44 / 50
页数:7
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