Diffusion-weighted MR imaging of bone marrow:: Differentiation of benign versus pathologic compression fractures

被引:286
作者
Baur, A
Stäbler, A
Brüning, R
Bartl, R
Krödel, A
Reiser, M
Deimling, M
机构
[1] Univ Munich, Dept Diagnost Radiol, D-81377 Munich, Germany
[2] Univ Munich, Dept Internal Med, D-81377 Munich, Germany
[3] Univ Munich, Dept Orthoped Surg, D-81377 Munich, Germany
[4] Siemens AG, Med Ctr, D-8520 Erlangen, Germany
关键词
magnetic resonance (MR); comparative studies; diffusion study; osteoporosis; spine; fractures; primary neoplasms;
D O I
10.1148/radiology.207.2.9577479
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To evaluate the usefulness of diffusion-weighted magnetic resonance (MR) imaging of bone marrow for differentiating between benign and pathologic vertebral compression fractures. MATERIALS AND METHODS: Thirty patients with 39 vertebral compression fractures were examined with MR imaging. Diffusion-weighted MR imaging was performed with a steady-state free precession sequence in 22 acute benign osteoporotic and/or traumatic fractures and 17 pathologic compression fractures. Biplanar radiographs, T1-weighted spin-echo (SE) MR images, and short inversion time inversion-recovery (STIR) MR images were available for all patients. The signal intensity characteristics were analyzed qualitatively and quantitatively (bone marrow contrast ratios and signal-to-noise ratios) for all sequences. RESULTS: At diffusion-weighted MR imaging, all benign vertebral compression fractures were hypo- to isointense to adjacent normal vertebral bodies. Pathologic compression fractures were hyperintense to normal vertebral bodies. Benign vertebral fractures had negative bone marrow contrast ratios at diffusion-weighted imaging, whereas pathologic vertebral fractures had positive values (P < .001). The difference in bone marrow contrast ratios for benign and pathologic compression fractures at T1-weighted SE and STIR imaging was not significant (P > .01). CONCLUSION: Diffusion-weighted MR imaging provided excellent distinction between pathologic and benign vertebral compression fractures.
引用
收藏
页码:349 / 356
页数:8
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