On-chip cavity-enhanced absorption spectroscopy using a white light-emitting diode and polymer mirrors

被引：30
|
作者：
Rushworth, Cathy M. [1 ]
Jones, Gareth [1 ]
Fischlechner, Martin [2 ,4 ]
Walton, Emma [3 ]
Morgan, Hywel [1 ]
机构：
[1] Univ Southampton, Sch Elect & Comp Sci, Southampton SO17 1BJ, Hants, England
[2] Univ Southampton, Inst Life Sci, Southampton SO17 1BJ, Hants, England
[3] Oxford Sci Pk, Sharp Labs Europe, Oxford OX4 4GB, England
[4] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England
来源：
LAB ON A CHIP | 2015年 / 15卷 / 03期
基金：
美国国家卫生研究院;
关键词：
RING-DOWN; LIQUID-PHASE; SEAWATER;
D O I：
10.1039/c4lc01264j
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We have developed a disposable microfluidic chip with integrated cavity mirrors comprised of two pieces of 3M Vikuiti (TM) enhanced specular reflector II (ESRII) film, for performing cavity-enhanced absorption spectroscopy with a white light-emitting diode (LED). Compared to measurements made with a chip without cavity mirrors, the absorption path length is enhanced by a maximum factor of 28 at 544 nm, and the sensitivity is enhanced by approximately 5 times, enabling micromolar range detection limits to be achieved in an optical path length of only 50 mu m.
引用
收藏
页码：711 / 717
页数：7
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