Management of Acute Ischemic Stroke

被引:22
作者
Abou-Chebl, Alex [1 ]
机构
[1] Univ Louisville, Sch Med, Dept Neurol, Louisville, KY 40202 USA
关键词
Acute stroke; Cerebral ischemia; Intracerebral hemorrhage; Thrombolysis; Intra-arterial therapy; Thrombectomy; AMERICAN-HEART-ASSOCIATION; TISSUE-PLASMINOGEN-ACTIVATOR; RANDOMIZED CONTROLLED-TRIAL; HEALTH-CARE PROFESSIONALS; PERIPHERAL VASCULAR-DISEASE; BRAIN ATTACK COALITION; SPECIAL WRITING GROUP; QUALITY-OF-CARE; RT-PA STROKE; DECOMPRESSIVE HEMICRANIECTOMY;
D O I
10.1007/s11886-013-0348-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute stroke affects about 800,000 patients annually in the US and is the leading cause of disability. It is a complex condition with multiple causes and requires comprehensive but rapid evaluation by stroke specialists working in institutions with well-organized stroke systems of care. Acute stroke treatment is focused on early revascularization with intravenous tPA for those with strokes under 3 hours duration or intra-arterial therapy for most others and those who cannot receive tPA. The latter is evolving rapidly with the advent of stent-retriever embolectomy devices that are poised to revolutionize stroke treatment. Recanalization is associated with neurological recovery in 33-50 % of patients. This also means that many patients may have devastating and life-threatening brain injury, which highlights the need for comprehensive care for the prevention and treatment of medical complications, management of cerebral edema and intracerebral hemorrhage.
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页数:8
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