Preoperative combination chemotherapy with S-1 and low dose cisplatin against highly advanced gastric carcinoma

被引：2

作者：

Saikawa, Y

Akasaka, Y

Kanai, T

Otani, Y

Kumai, K

Kubota, T

Kitajima, M

机构：

[1] Keio Univ, Dept Surg, Sch Med, Shinjuku Ku, Tokyo 1608582, Japan

[2] Toho Univ, Sch Med, Dept Pathol 2, Ohta Ku, Tokyo 1438540, Japan

[3] Hiratsuka City Hosp, Dept Surg, Hiratsuka, Kanagawa 2540065, Japan

来源：

ONCOLOGY REPORTS | 2003年 / 10卷 / 02期

关键词：

preoperative chemotherapy; gastric cancer; S-1; cisplatin;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We performed preoperative chemotherapy with S-1 and low-dose CDDP (TSLD) to treat 9 patients of highly advanced gastric cancer. Five cases showed significant effect with severe fibrosis diagnosed as grade 1b-2 effect in histology, and all 9 cases showed at least grade la effect in either primary lesion or lymph node. While toxicity of less than grade 3 (gastrointestinal disorder and/or bone marrow suppression) were observed in 5 out of 9 cases (55.6%), no symptom was observed in 3 out of the 5 patients. We conclude that the TSLD is useful to control highly advanced gastric cancer.

引用

页码：381 / 386

页数：6

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