Design, Synthesis, and Functionalization of Nanomaterials for Therapeutic Drug Delivery

被引：8
作者：
Grandhi, Taraka Sai Pavan [1 ]
Rege, Kaushal [1 ,2 ]
机构：
[1] Sch Biol & Hlth Syst Engn, Tempe, AZ 85287 USA
[2] Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA
来源：
NANOMATERIAL: IMPACTS ON CELL BIOLOGY AND MEDICINE | 2014年 / 811卷
基金：
美国国家科学基金会;
关键词：
Drug-delivery; Micelles; Liposomes; PLGA-nanoparticles; FDA; Multifunctional nanomedicine; Cancer; BLOCK-COPOLYMER MICELLES; POLYMERIC MICELLES; IN-VIVO; INTRACELLULAR DELIVERY; LIPOSOMAL DOXORUBICIN; POLY(ETHYLENE GLYCOL); FUSOGENIC LIPOSOMES; TARGETED DELIVERY; CONTRAST AGENTS; CANCER-CELLS;
D O I：
10.1007/978-94-017-8739-0_9
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Nanomaterials have the potential to solve some of the toughest challenges facing modern medicine. Their unique optical, magnetic and chemical properties at the nanoscale make them different from their macroscale counterparts. Successful application of nanomaterials can revolutionize therapeutics, diagnostics and imaging in several biomedical applications. Self-assembled amphiphilic polymeric nanoparticles have been employed to carry poorly soluble chemotherapeutic drugs. Loading of anticancer chemotherapeutic drugs into self assembled polymeric nanoparticles have shown to increase their circulation time, tumor localization and therapeutic potential. This book chapter provides an introductory discussion to organic nanotechnologies for drug delivery. Promising advances in the field of nanomedicine will be discussed and an outlook to the future will be provided.
引用
收藏
页码：157 / 182
页数：26
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