A history estimate and evolutionary analysis of rabies virus variants in China

被引:23
作者
Ming, Pinggang [1 ]
Yan, Jiaxin [1 ]
Rayner, Simon [2 ]
Meng, Shengli [1 ]
Xu, Gelin [1 ]
Tang, Qing [3 ]
Wu, Jie [1 ]
Luo, Jing [1 ]
Yang, Xiaoming [1 ]
机构
[1] Wuhan Inst Biol Prod, Dept Genet Engn, Wuhan 430060, Peoples R China
[2] Chinese Acad Sci, Wuhan Inst Virol, Dept Bioinformat, Wuhan 430071, Peoples R China
[3] China CDC, Natl Inst Viral Dis Control & Prevent, State Key Lab Mol Virol & Genet Engn, Beijing 100052, Peoples R China
基金
国家高技术研究发展计划(863计划);
关键词
DOG RABIES; DYNAMICS; PHYLOGEOGRAPHY; EPIDEMIOLOGY;
D O I
10.1099/vir.0.016436-0
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
To investigate the evolutionary dynamics of rabies virus (RABV) in China, we collected and sequenced 55 isolates sampled from 14 Chinese provinces over the last 40 years and performed a coalescent-based analysis of the G gene. This revealed that the RABV currently circulating in China is composed of three main groups. Bayesian coalescent analysis estimated the date of the most recent common ancestor for the current RABV Chinese strains to be 1412 (with a 95 % confidence interval of 1006-1736). The estimated mean substitution rate for the G gene sequences (3.961 x 10(-4) substitutions per site per year) was in accordance with previous reports for RABV.
引用
收藏
页码:759 / 764
页数:6
相关论文
共 26 条
[1]  
[Anonymous], 2001, RABIES RABIES VACCIN
[2]   Evidence of two Lyssavirus phylogroups with distinct pathogenicity and immunogenicity [J].
Badrane, H ;
Bahloul, C ;
Perrin, P ;
Tordo, N .
JOURNAL OF VIROLOGY, 2001, 75 (07) :3268-3276
[3]  
Bai Xian-He, 1994, Zhonghua Weishengquxue He Mianyixue Zazhi, V14, P10
[4]   The origin and phylogeography of dog rabies virus [J].
Bourhy, Herve ;
Reynes, Jean-Marc ;
Dunham, Eleca J. ;
Dacheux, Laurent ;
Larrous, Florence ;
Huong, Vu Thi Oue ;
Xu, Gelin ;
Yan, Jiaxin ;
Miranda, Mary Elizabeth G. ;
Holmes, Edward C. .
JOURNAL OF GENERAL VIROLOGY, 2008, 89 :2673-2681
[5]   The evolutionary history and dynamics of bat rabies virus [J].
Davis, Patricia L. ;
Bourhy, Herve ;
Holmes, Edward C. .
INFECTION GENETICS AND EVOLUTION, 2006, 6 (06) :464-473
[6]   Phylogeography, population dynamics, and molecular evolution of European bat lyssaviruses [J].
Davis, PL ;
Holmes, EC ;
Larrous, F ;
Van der Poel, WHM ;
Tjornehoj, K ;
Alonso, WJ ;
Bourhy, H .
JOURNAL OF VIROLOGY, 2005, 79 (16) :10487-10497
[7]   Inference of viral evolutionary rates from molecular sequences [J].
Drummond, A ;
Pybus, OG ;
Rambaut, A .
ADVANCES IN PARASITOLOGY, VOL 54: THE EVOLUTION OF PARASITISM-A PHYLOGENETIC PERSPECTIVE, 2003, 54 :331-358
[8]  
Drummond AJ, 2002, GENETICS, V161, P1307
[9]   Synchronous cycles of domestic dog rabies in sub-Saharan Africa and the impact of control efforts [J].
Hampson, Katie ;
Dushoff, Jonathan ;
Bingham, John ;
Bruckner, Gideon ;
Ali, Y. H. ;
Dobson, Andy .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (18) :7717-7722
[10]   Genetic constraints and the adaptive evolution of rabies virus in nature [J].
Holmes, EC ;
Woelk, CH ;
Kassis, R ;
Bourhy, H .
VIROLOGY, 2002, 292 (02) :247-257