Analysis of Hearing Preservation After Endolymphatic Mastoid Sac Surgery for Meniere's Disease

被引:7
作者
Sun, Gordon H. [1 ]
Leung, Randal [1 ]
Samy, Ravi N. [1 ]
McAfee, Jacob S. [2 ]
Hearst, Matthew J. [3 ]
Savage, Christopher R. [1 ]
Choo, Daniel I. [1 ]
Pensak, Myles L. [1 ]
机构
[1] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Dept Otolaryngol Head & Neck Surg, Cincinnati, OH 45267 USA
[2] Eastern Virginia Med Sch, Dept Otolaryngol Head & Neck Surg, Norfolk, VA 23501 USA
[3] So Maine Med Ctr, Biddeford, ME USA
关键词
Meniere's disease; endolymphatic hydrops; hearing loss; pure-tone average; speech discrimination score; speech reception threshold; endolymphatic sac surgery; INTRATYMPANIC GENTAMICIN; VEIN DECOMPRESSION; MEDICAL THERAPY; SHUNT SURGERY; GUINEA-PIG; FOLLOW-UP; HYDROPS; DUCT; PATHOGENESIS; STEREOCILIA;
D O I
10.1002/lary.20787
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objectives/Hypothesis: Comparison of audiometric outcomes between patients with definite Meniere's disease who underwent endolymphatic mastoid sac surgery (EMSS) following failed medical therapy and patients who underwent medical therapy only. Study Design: Retrospective chart review of 456 consecutive patients between 1997 and 2006. Methods: Outcome measures were changes in pure-tone average (PTA), word recognition score (WRS), and speech reception threshold (SRT). Results: Of 58 qualified patients, 29 who underwent EMSS after failing medical therapy showed a 4 dB decrease in PTA, a 2% increase in VMS, and a 2 dB decrease in SRT. Twenty-nine patients treated with medical therapy only demonstrated a 1 dB PTA increase, 2% WRS improvement, and 2 dB SRT improvement. No significant difference was noted between the medically and surgically managed patients in terms of changes in PTA (P = .34) or WRS (P = .95) after treatment. Of all patients in the study, 60% had no clinically significant change in hearing, whereas 24% improved and 16% worsened. The distribution of post-treatment hearing changes between the medical and surgical groups was statistically insignificant (P = .17). Conclusions: The changes in PTA and WRS among patients with Meniere's disease managed with medical therapy or EMSS were not statistically significant. Although performing EMSS to treat the vertigo of Meniere's disease does not appear to be associated with an increased risk of deteriorating auditory function after treatment, surgery also does not confer an increased likelihood of stabilizing or improving hearing.
引用
收藏
页码:591 / 597
页数:7
相关论文
共 40 条
[1]  
[Anonymous], 1995, OTOLARYNGOL HEAD NEC, V113, P181
[2]   Viral theory for Meniere's disease and endolymphatic hydrops: Overview and new therapeutic options for viral labyrinthitis [J].
Arenberg, IK ;
Lemke, C ;
Shambaugh, GE .
IMMUNOLOGIC DISEASES OF THE EAR, 1997, 830 :306-313
[3]  
ARENBERG IK, 1987, AM J OTOL, V8, P335
[4]   Spiral Ganglion Degeneration Patterns in Endolymphatic Hydrops [J].
Bixenstine, Paul J. ;
Maniglia, Mauricio P. ;
Vasanji, Amit ;
Alagramam, Kumar N. ;
Megerian, Cliff A. .
LARYNGOSCOPE, 2008, 118 (07) :1217-1223
[5]   Long-term vertigo control in patients after intratympanic gentamicin instillation for Meniere's disease [J].
Bodmer, Daniel ;
Morong, Sharon ;
Stewart, Craig ;
Alexander, Ashlin ;
Chen, Joseph M. ;
Nedzelski, Julian M. .
OTOLOGY & NEUROTOLOGY, 2007, 28 (08) :1140-1144
[6]   Longitudinal results with intratympanic dexamethasone in the treatment of Meniere's disease [J].
Boleas-Aguirre, Maria Soledad ;
Lin, Frank R. ;
Della Santina, Charles C. ;
Minor, Lloyd B. ;
Carey, John P. .
OTOLOGY & NEUROTOLOGY, 2008, 29 (01) :33-38
[7]   Endolymphatic mastoid shunt versus endolymphatic sac decompression for Meniere's disease [J].
Brinson, George M. ;
Chen, Douglas A. ;
Arriaga, Moises A. .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2007, 136 (03) :415-421
[8]  
BROWN JS, 1983, LARYNGOSCOPE, V93, P1419
[9]   Outcome-based assessment of endolymphatic sac decompression for Meniere's disease using the Meniere's disease outcome questionnaire: A review of 90 patients [J].
Convert, Cyrille ;
Franco-Vidal, Valerie ;
Bebear, Jean-Pierre ;
Darrouzet, Vincent .
OTOLOGY & NEUROTOLOGY, 2006, 27 (05) :687-696
[10]   Intratympanic gentamicin therapy for intractable Meniere's disease [J].
De Beer, Lieke ;
Stokroos, Robert ;
Kingma, Herman .
ACTA OTO-LARYNGOLOGICA, 2007, 127 (06) :605-612