Rapidly progressive glomerulonephritis due to anti-glomerular basement membrane disease accompanied by IgA nephropathy: a case report

被引：10
|
作者：
Gao, Bixia [1 ]
Li, Mingxi [1 ]
Xia, Wenli [1 ]
Wen, Yubin [1 ]
Qu, Zhen [2 ]
机构：
[1] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Nephrol, Beijing 100005, Peoples R China
[2] Peking Univ, Inst Nephrol, Hosp 1, Dept Nephrol, Beijing 100871, Peoples R China
来源：
CLINICAL NEPHROLOGY | 2014年 / 81卷 / 02期
关键词：
anti-glomerular basement membrane disease; IgA nephropathy; autoantibody; GOODPASTURES-SYNDROME; IDENTIFICATION; ANTIBODIES; ANTIGEN; CHAIN;
D O I：
10.5414/CN107213
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Anti-glomerular basement membrane (anti-GBM) disease is characterized by autoantibodies against antigenic site on type IV collagen of the GBM. The coexistence of anti-GBM disease and other immune complex mediated glomerulonephritis is common. Herein, we describe a patient presented with rapidly progressive glomerulonephritis, who was diagnosed as IgA-mediated nephropathy and was found to have abundant serum anti-glomerular basement membrane IgG antibodies. The patient's renal function improved considerably with intensive immunosuppressive therapy.
引用
收藏
页码：138 / 141
页数：4
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