Rapidly progressive glomerulonephritis due to anti-glomerular basement membrane disease accompanied by IgA nephropathy: a case report

被引：10

作者：

Gao, Bixia ^{[1
]}

Li, Mingxi ^{[1
]}

Xia, Wenli ^{[1
]}

Wen, Yubin ^{[1
]}

Qu, Zhen ^{[2
]}

机构：

[1] Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Nephrol, Beijing 100005, Peoples R China

[2] Peking Univ, Inst Nephrol, Hosp 1, Dept Nephrol, Beijing 100871, Peoples R China

来源：

CLINICAL NEPHROLOGY | 2014年 / 81卷 / 02期

关键词：

anti-glomerular basement membrane disease; IgA nephropathy; autoantibody; GOODPASTURES-SYNDROME; IDENTIFICATION; ANTIBODIES; ANTIGEN; CHAIN;

D O I：

10.5414/CN107213

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Anti-glomerular basement membrane (anti-GBM) disease is characterized by autoantibodies against antigenic site on type IV collagen of the GBM. The coexistence of anti-GBM disease and other immune complex mediated glomerulonephritis is common. Herein, we describe a patient presented with rapidly progressive glomerulonephritis, who was diagnosed as IgA-mediated nephropathy and was found to have abundant serum anti-glomerular basement membrane IgG antibodies. The patient's renal function improved considerably with intensive immunosuppressive therapy.

引用

页码：138 / 141

页数：4

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