The Multidimensional Assessment for Pediatric Patients in Radiotherapy (MAP-RT) Tool for Customized Treatment Preparation: RADAR Project

被引:11
作者
Chiesa, Silvia [1 ]
Marconi, Elisa [1 ,2 ]
Dinapoli, Nicola [1 ]
Sanfilippo, Maria Zoe [3 ]
Ruggiero, Antonio [3 ,4 ]
Mastronuzzi, Angela [5 ]
Panza, Giulia [3 ]
Serra, Annalisa [5 ]
Massaccesi, Mariangela [1 ]
Cacchione, Antonella [5 ]
Bartoli, Francesco Beghella [1 ]
Chieffo, Daniela Pia Rosaria [2 ]
Gambacorta, Maria Antonietta [1 ,3 ]
Valentini, Vincenzo [1 ,3 ]
Balducci, Mario [1 ,3 ]
机构
[1] Fdn Policlin Univ Agostino Gemelli IRCCS, UOC Radioterapia Oncol, Dipartimento Diagnost Immagini Radioterapia Oncol, Rome, Italy
[2] Fdn Policlin Univ Agostino Gemelli IRCCS, UOS Psicol Clin, Rome, Italy
[3] Univ Cattolica Sacro Cuore, Rome, Italy
[4] Fdn Policlin Univ A Gemelli IRCCS, UOC Pediat Oncol, Dept Woman & Child Hlth & Publ Hlth, Rome, Italy
[5] IRCCS Bambino Gesu Childrens Hosp, Dept Paediat Haematol Oncol, Rome, Italy
关键词
radiotherapy; distress; anesthesia; pediatrics; psychological support; children;
D O I
10.3389/fonc.2021.621690
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aims: Pediatric patients may experience considerable distress during radiotherapy. Combining psychological interventions with standard therapies can reduce the need for sedation. The RADAR Project aims to use a systematic method of recording data that can reveal patients' difficulties and fragility during treatment. In this context, the aim of our study was to investigate the ability of a multidimensional assessment tool (M.A.P.-RT schedule) to predict the need for sedation during radiotherapy. The schedule, which is administered during the first evaluation, was created to collect information on patients and their families in a standardized way. Materials and Methods: The study enrolled pediatric patients (aged 0-18 years or 18-21 with cognitive impairment). Data were collected by means of the M.A.P.-RT module; this explores various thematic areas, and is completed by the radiation oncologist, psychologist and nurse during their first evaluation. Features were selected by means of the Boruta method (random forest classifier), and the totals of the significant partial scores on each subsection of the module were inserted into a logistic model in order to test for their correlation with the use of anesthesia and with the frequency of psychological support. The results of logistic regression (LR) were used to identify the best predictors. The AUC was used to identify the best threshold for the scores in the evaluation. Results: A total of 99 patients were considered for this analysis. The feature that best predicted both the need for anesthesia and the frequency of psychological support was the total score (TS), the AUC of the ROC being 0.9875 for anesthesia and 0.8866 for psychological support. Conclusion: During the first evaluation, the M.A.P.-RT form can predict the need for anesthesia in pediatric patients, and is a potential tool for personalizing therapeutic and management procedures.
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页数:10
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