The myths and realities of hemochromatosis

被引:18
作者
Beaton, Melanie D. [1 ]
Adams, Paul C. [1 ]
机构
[1] London Hlth Sci Ctr, Dept Med, London, ON N6A 5A5, Canada
关键词
genetic testing; hemochromatosis; iron;
D O I
10.1155/2007/619401
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hemochromatosis is a common genetic condition and yet there are still a number of misperceptions surrounding the diagnosis and management of this condition. Hemochromatosis affects both men and women. Typical patients do not have alcoholism or viral hepatitis, and often have normal liver enzymes. Clinical expression is highly variable. Genetic testing is widely available and particularly useful in family Studies. Hemochromatosis can be readily diagnosed and treated. The purpose of the present review is to address the medical myths and misconceptions of hemochromatosis.
引用
收藏
页码:101 / 104
页数:4
相关论文
共 32 条
[1]   Liver diseases in the hemochromatosis and iron overload screening study [J].
Adams, Paul C. ;
Passmore, Leah ;
Chakrabarti, Subrata ;
Reboussin, David M. ;
Acton, Ronald T. ;
Barton, James C. ;
Mclaren, Gordon D. ;
Eckfeldt, John H. ;
Dawkins, Fitzroy W. ;
Gordeuk, Victor R. ;
Harris, Emily L. ;
Leiendecker-Foster, Catherine ;
Gossman, Elaine ;
Sholinsky, Phyliss .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (07) :918-923
[2]   Alcoholism in hereditary hemochromatosis revisited: Prevalence and clinical consequences among homozygous siblings [J].
Adams, PC ;
Agnew, S .
HEPATOLOGY, 1996, 23 (04) :724-727
[3]   Hemochromatosis and iron-overload screening in a racially diverse population [J].
Adams, PC ;
Reboussin, DM ;
Barton, JC ;
McLaren, CE ;
Eckfeldt, JH ;
McLaren, GD ;
Dawkins, FW ;
Acton, RT ;
Harris, EL ;
Gordeuk, VR ;
Leiendecker-Foster, C ;
Speechley, M ;
Snively, BM ;
Holup, JL ;
Thomson, E ;
Sholinsky, P ;
Acton, RT ;
Barton, JC ;
Dixon, D ;
Rivers, CA ;
Tucker, D ;
Ware, JC ;
McLaren, CE ;
McLaren, GD ;
Anton-Culver, H ;
Baca, JA ;
Bent, TC ;
Brunner, LC ;
Dao, MM ;
Jorgensen, KS ;
Kuniyoshi, J ;
Le, HD ;
Masatsugu, MK ;
Meyskens, FL ;
Morohashi, D ;
Nguyen, HP ;
Panagon, SN ;
Phung, C ;
Raymundo, V ;
Ton, T ;
Walker, AP ;
Wenzel, LB ;
Ziogas, A ;
Adams, PC ;
Bloch, E ;
Chakrabarti, S ;
Fleischhauer, A ;
Harrison, H ;
Jia, K ;
Larson, S .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (17) :1769-1778
[4]   Hemochromatosis case definition: out of focus? [J].
Adams, PC .
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY, 2006, 3 (04) :178-179
[5]   RATE OF IRON REACCUMULATION FOLLOWING IRON DEPLETION IN HEREDITARY HEMOCHROMATOSIS - IMPLICATIONS FOR VENESECTION THERAPY [J].
ADAMS, PC ;
KERTESZ, AE ;
VALBERG, LS .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 1993, 16 (03) :207-210
[6]   A primer for predicting risk of disease in HFE-linked Hemochromatosis [J].
Adams, PC ;
Walker, AP ;
Acton, RT .
GENETIC TESTING, 2001, 5 (04) :311-316
[7]  
Adams PC, 1997, HEPATOLOGY, V25, P162, DOI 10.1002/hep.510250130
[8]  
ADAMS PC, 1990, CAN J GASTROENTEROL, V4, P160
[9]   Iron in nonhemochromatotic liver disorders [J].
Alla, V ;
Bonkovsky, HL .
SEMINARS IN LIVER DISEASE, 2005, 25 (04) :461-472
[10]   Hemochromatosis mutations in the general population: iron overload progression rate [J].
Andersen, RV ;
Tybjaerg-Hansen, A ;
Appleyard, M ;
Birgens, H ;
Nordestgaard, BG .
BLOOD, 2004, 103 (08) :2914-2919