Hematopoietic stem cell transplantation in multiple myeloma

被引：11

作者：

Pant, Shubham

Copelan, Edward A.

机构：

[1] Cleveland Clin Fdn, Dept Hematol Oncol & Blood Disorders, Taussig Canc Ctr, Cleveland, OH 44195 USA

[2] Ohio State Univ, Div Hematol & Oncol, Columbus, OH 43210 USA

来源：

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | 2007年 / 13卷 / 08期

关键词：

multiple myeloma; hematopoietic stem cell transplantation;

D O I：

10.1016/j.bbmt.2007.05.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

High-dose therapy and autologous hematopoietic stem cell transplantation are standard early treatment of patients with multiple myeloma. Tandem transplantation appears to provide additional benefit, particularly in patients with limited response to initial transplantation. Myeloablative allogeneic transplantation provides the only potential for cure, but has been largely abandoned because of high mortality rates. Newer and better induction regimens, rigorous analysis of results with autologous and allogeneic transplantation, and the development of risk-adapted stratification provide the impetus for this critical evaluation of the role of hematopoietic stem cell transplantation in multiple myeloma. (c) 2007 American Society for Blood and Marrow Transplantation

引用

页码：877 / 885

页数：9

共 91 条

[1] Clinical outcomes with intensive therapy for patients with primary resistant multiple myeloma [J].

Alexanian, R ;

Weber, D ;

Delasalle, K ;

Handy, B ;

Champlin, R ;

Giralt, S .

BONE MARROW TRANSPLANTATION, 2004, 34 (03) :229-234

[2]

ALEXANIAN R, 1986, ANN INTERN MED, V105, P8, DOI 10.7326/0003-4819-105-1-8

[3]

ALEXANIAN R, 1989, EUR J HAEMATOL, V43, P140

[4]

ALEXANIAN R, 1992, BLOOD, V80, P887

[5] Long-term follow-up of gene-marked CD34+ cells after autologous stem cell transplantation for multiple myeloma [J].

Alici, E. ;

Bjorkstrand, B. ;

Treschow, A. ;

Aints, A. ;

Smith, C. I. E. ;

Gahrton, G. ;

Dilber, M. S. .

CANCER GENE THERAPY, 2007, 14 (03) :227-232

[6] T-cell-depleted allogeneic bone marrow transplantation followed by donor lymphocyte infusion in patients with multiple myeloma: induction of graft-versus-myeloma effect [J].

Alyea, E ;

Weller, E ;

Schlossman, R ;

Canning, C ;

Webb, I ;

Doss, D ;

Mauch, P ;

Marcus, K ;

Fisher, D ;

Freeman, A ;

Parikh, B ;

Gribben, J ;

Soiffer, R ;

Ritz, J ;

Anderson, K .

BLOOD, 2001, 98 (04) :934-939

[7]

[Anonymous], 1998, J Clin Oncol, V16, P3832

[8] Results of autologous and allogeneic hematopoietic cell transplant therapy for multiple myeloma [J].

Arora, M ;

McGlave, PB ;

Burns, LJ ;

Miller, JS ;

Barke, JN ;

Defor, TE ;

Weisdorf, DJ .

BONE MARROW TRANSPLANTATION, 2005, 35 (12) :1133-1140

[9] Single versus double autologous stem-cell transplantation for multiple myeloma [J].

Attal, M ;

Harousseau, JL ;

Facon, T ;

Guilhot, F ;

Doyen, C ;

Fuzibet, JG ;

Monconduit, M ;

Hulin, C ;

Caillot, D ;

Bouabdallah, R ;

Voillat, L ;

Sotto, JJ ;

Grosbois, B ;

Bataille, R .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (26) :2495-2502

[10] A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma [J].

Attal, M ;

Harousseau, JL ;

Stoppa, AM ;

Sotto, JJ ;

Fuzibet, JG ;

Rossi, JF ;

Casassus, P ;

Maisonneuve, H ;

Facon, T ;

Ifrah, N ;

Payen, C ;

Bataille, R .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (02) :91-97

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