Seeing the future of bioactive lipid drug targets

被引:13
作者
Evans, Jilly F. [1 ]
Hutchinson, John H. [1 ]
机构
[1] Amira Pharmaceut, San Diego, CA USA
关键词
NUCLEAR RECEPTORS; DISEASES; INFLAMMATION; DISCOVERY; LESSONS; LIGAND; LUNG;
D O I
10.1038/nchembio.394
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bioactive lipid signaling allows individual cells within the body to 'see' the surrounding environment and to respond in ways that will benefit the whole organism. Successful drug development for bioactive lipid targets requires a deep knowledge of the biology and pathobiology of each specific lipid signaling pathway.
引用
收藏
页码:476 / 479
页数:4
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