Anatomical measurements of porcine lumbar vertebrae

被引:75
作者
Dath, R.
Ebinesan, A. D.
Porter, K. M.
Miles, A. W.
机构
[1] Univ Birmingham, Hosp NHS Trust, Birmingham B15 2TT, W Midlands, England
[2] Univ Bath, Ctr Orthopaed Biomech, Dept Mech Engn, Bath BA2 7AY, Avon, England
关键词
comparative anatomy; porcine model; spinal instrumentation;
D O I
10.1016/j.clinbiomech.2007.01.014
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Background. Porcine spines are frequently used as an alternative to human specimens for spinal implant testing. Morphometric data of the normal porcine lumbar vertebrae are lacking at this time, yet these data are crucial for application to such studies. This study provides such a database and highlights the differences between porcine and human specimens. Methods. All the lumbar vertebrae (L1-L6) from six adult (18-24 month old, 60-80 kg) male porcine spines were used in our study (n = 36). A total of 15 anatomical parameters from each vertebra were measured by two observers. Linear parameters were measured using digital calipers. The mean, standard deviation and standard error of mean were calculated using Microsoft Excel. Results from our study were compared with available data on human vertebra. Findings. Compared to the human vertebrae, there were several anatomical differences in the porcine thoracolumbar vertebrae including smaller end plate area, larger pedicles, taller and narrower vertebral bodies, narrower spinal canals and smaller spinous process lengths. Interpretation. Our results provide a database of anatomical measurements for porcine lumbar vertebrae and highlight their differences with human vertebrae. Porcine vertebrae may be used as an alternative to human specimen if these differences are taken into account. Studies which involve testing implants such as interbody cages, disc replacements and pedicle screw rod systems in porcine spines should match implant size appropriately. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:607 / 613
页数:7
相关论文
共 21 条
[1]   Interspecies differences in bone composition, density, and quality:: Potential implications for in vivo bone research [J].
Aerssens, J ;
Boonen, S ;
Lowet, G ;
Dequeker, J .
ENDOCRINOLOGY, 1998, 139 (02) :663-670
[2]   Comparative and functional anatomy of the mammalian lumbar spine [J].
Boszczyk, BM ;
Boszczyk, AA ;
Putz, R .
ANATOMICAL RECORD, 2001, 264 (02) :157-168
[3]   Comparative anatomy of the porcine and human thoracic spines with reference to thoracoscopic surgical techniques [J].
Bozkus, H ;
Crawford, NR ;
Chamberlain, RH ;
Valenzuela, TD ;
Espinoza, A ;
Yüksel, Z ;
Dickman, CA .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2005, 19 (12) :1652-1665
[4]   Titanium-alloy enhances bone-pedicle screw fixation:: mechanical and histomorphometrical results of titanium-alloy versus stainless steel [J].
Christensen, FB ;
Dalstra, M ;
Sejling, F ;
Overgaard, S ;
Bünger, C .
EUROPEAN SPINE JOURNAL, 2000, 9 (02) :97-103
[5]   AN ANATOMICAL COMPARISON OF THE HUMAN AND BOVINE THORACOLUMBAR SPINE [J].
COTTERILL, PC ;
KOSTUIK, JP ;
DANGELO, G ;
FERNIE, GR ;
MAKI, BE .
JOURNAL OF ORTHOPAEDIC RESEARCH, 1986, 4 (03) :298-303
[6]   Biomechanical evaluation of lumbosacral reconstruction techniques for spondylolisthesis -: An in vitro porcine model [J].
Cunningham, BW ;
Lewis, SJ ;
Long, J ;
Dmitriev, AE ;
Linville, DA ;
Bridwell, KH .
SPINE, 2002, 27 (21) :2321-2327
[7]   COMPOSITION OF TRABECULAR + CORTICAL BONE [J].
GONG, JK ;
ARNOLD, JS ;
COHN, SH .
ANATOMICAL RECORD, 1964, 149 (03) :325-&
[8]  
Kumar N, 2000, ANAT RECORD, V260, P189, DOI 10.1002/1097-0185(20001001)260:2<189::AID-AR80>3.0.CO
[9]  
2-N
[10]   Distribution and regional strength of trabecular bone in the porcine lumbar spine [J].
Lin, RM ;
Tsai, KH ;
Chang, GL .
CLINICAL BIOMECHANICS, 1997, 12 (05) :331-336