Bioactive Peptides

被引:374
作者
Daliri, Eric Banan-Mwine [1 ]
Oh, Deog H. [1 ]
Lee, Byong H. [1 ,2 ]
机构
[1] Kangwon Natl Univ, Dept Food Sci & Biotechnol, Chunchon 24341, South Korea
[2] McGill Univ, Dept Microbiol Immunol, Montreal, PQ H3A 0G4, Canada
关键词
functional foods; antihypertensive peptides; bioactivity; cytotoxicity; CONVERTING-ENZYME ACE; IV-INHIBITORY PEPTIDES; 3 ANTIOXIDANT PEPTIDES; LONG-TERM INTAKE; PROTEIN-DERIVED PEPTIDES; BEAN PHASEOLUS-VULGARIS; ELECTRIC-FIELD PEF; IN-VITRO; ANTIHYPERTENSIVE PEPTIDES; ANTIMICROBIAL PEPTIDE;
D O I
10.3390/foods6050032
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The increased consumer awareness of the health promoting effects of functional foods and nutraceuticals is the driving force of the functional food and nutraceutical market. Bioactive peptides are known for their high tissue affinity, specificity and efficiency in promoting health. For this reason, the search for food-derived bioactive peptides has increased exponentially. Over the years, many potential bioactive peptides from food have been documented; yet, obstacles such as the need to establish optimal conditions for industrial scale production and the absence of well-designed clinical trials to provide robust evidence for proving health claims continue to exist. Other important factors such as the possibility of allergenicity, cytotoxicity and the stability of the peptides during gastrointestinal digestion would need to be addressed. This review discusses our current knowledge on the health effects of food-derived bioactive peptides, their processing methods and challenges in their development.
引用
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页码:1 / 21
页数:21
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共 180 条
  • [1] Angiotensin-converting enzyme inhibition and antioxidant activity of commercial dairy starter cultures
    Abd El-Fattah, Alaa
    Sakr, Sally
    El-Dieb, Samia
    Elkashef, Hany
    [J]. FOOD SCIENCE AND BIOTECHNOLOGY, 2016, 25 (06) : 1745 - 1751
  • [2] Angiotensin I-converting enzyme inhibitory activity and antioxidant capacity of bioactive peptides derived from enzymatic hydrolysis of buffalo milk proteins
    Abdel-Hamid, Mahmoud
    Otte, Jeanette
    De Gobba, Cristian
    Osman, Ali
    Hamad, Essam
    [J]. INTERNATIONAL DAIRY JOURNAL, 2017, 66 : 91 - 98
  • [3] Controlled Enzymatic Hydrolysis: A New Strategy for the Discovery of Antimicrobial Peptides
    Adje, Estelle Yaba
    Balti, Rafik
    Lecouturier, Didier
    Kouach, Mostafa
    Dhulster, Pascal
    Guillochon, Didier
    Nedjar-Arroume, Naima
    [J]. PROBIOTICS AND ANTIMICROBIAL PROTEINS, 2013, 5 (03) : 176 - 186
  • [4] Assessment of multifunctional activity of bioactive peptides derived from fermented milk by specific Lactobacillus plantarum strains
    Aguilar-Toala, J. E.
    Santiago-Lopez, L.
    Peres, C. M.
    Peres, C.
    Garcia, H. S.
    Vallejo-Cordoba, B.
    Gonzalez-Cordova, A. F.
    Hernandez-Mendoza, A.
    [J]. JOURNAL OF DAIRY SCIENCE, 2017, 100 (01) : 65 - 75
  • [5] Bioprocess challenges to the isolation and purification of bioactive peptides
    Agyei, Dominic
    Ongkudon, Clarence M.
    Wei, Chan Yi
    Chan, Alan S.
    Danquah, Michael K.
    [J]. FOOD AND BIOPRODUCTS PROCESSING, 2016, 98 : 244 - 256
  • [6] The Effect of Busulfan on Body Weight, Testis Weight and MDA Enzymes in Male Rats
    Ahar, Nasibeh Hosseini
    Khaki, Arash
    Akbari, Ghasem
    Novin, Marefat Ghaffari
    [J]. INTERNATIONAL JOURNAL OF WOMENS HEALTH AND REPRODUCTION SCIENCES, 2014, 2 (05): : 316 - 319
  • [7] Statin Intolerance
    Ahmad, Zahid
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2014, 113 (10) : 1765 - 1771
  • [8] ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORY PEPTIDES FROM WHEY FERMENTED BY LACTOBACILLUS SPECIES
    Ahn, J. E.
    Park, S. Y.
    Atwal, A.
    Gibbs, B. F.
    Lee, B. H.
    [J]. JOURNAL OF FOOD BIOCHEMISTRY, 2009, 33 (04) : 587 - 602
  • [9] Alamdari E. Kamali, 2017, J FOOD BIOSCI TECHNO, V7, P49
  • [10] Extraction, optimisation and characterisation of phenolics from Thymus vulgaris L.: phenolic content and profiles in relation to antioxidant, antidiabetic and antihypertensive properties
    Alu'datt, Muhammad H.
    Rababah, Taha
    Johargy, Ayman
    Gammoh, Sana
    Ereifej, Khalil
    Alhamad, Mohammad N.
    Brewer, Mary Susan
    Saati, Abdullah A.
    Kubow, Stan
    Rawshdeh, Mervat
    [J]. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2016, 51 (03) : 720 - 730