Highly Selective Hydroiodation of Alkynes Using an Iodine-Hydrophosphine Binary System

被引：55

作者：

Kawaguchi, Shin-ichi ^{[1
]}

Ogawa, Akiya ^{[1
]}

机构：

[1] Osaka Prefecture Univ, Dept Appl Chem, Grad Sch Engn, Naka Ku, Osaka 5998531, Japan

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 09期

基金：

日本学术振兴会;

关键词：

ALKENES; ALCOHOLS; IODIDES; HYDROIODINATION; IODINATION; GENERATION; HALIDES; KETONES; ESTERS; I-2;

D O I：

10.1021/ol1005246

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel hydroiodation of alkynes (1) using an iodine/hydrophosphine binary system takes place regioselectively to provide the corresponding Markovnikov-type adducts (2) in good yield. This hydroiodation is advantageous in terms of mild conditions, convenient operation, and tolerance to various functional groups.

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收藏

页码：1893 / 1895

页数：3

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