Lymphatic Dysregulation in Patients With Heart Failure JACC Review Topic of the Week

被引:48
作者
Fudim, Marat [1 ,2 ]
Salah, Husam M. [3 ]
Sathananthan, Janarthanan [4 ,5 ]
Bernier, Mathieu [6 ]
Pabon-Ramos, Waleska [7 ]
Schwartz, Robert S. [8 ]
Rodes-Cabau, Josep [6 ,9 ]
Cote, Francois [10 ]
Khalifa, Abubaker [11 ]
Virani, Sean A. [4 ,5 ]
Patel, Manesh R. [1 ,2 ]
机构
[1] Duke Univ, Med Ctr, Dept Med, Div Cardiol, Durham, NC USA
[2] Duke Clin Res Inst, Durham, NC USA
[3] Univ Arkansas Med Sci, Dept Med, Little Rock, AR 72205 USA
[4] Univ British Columbia, Ctr Cardiovasc Innovat, Vancouver, BC, Canada
[5] Univ British Columbia, Div Cardiol, Vancouver, BC, Canada
[6] Laval Univ, Quebec Heart & Lung Inst, Quebec City, PQ, Canada
[7] Duke Univ, Med Ctr, Dept Radiol, Div Intervent Radiol, Durham, NC USA
[8] Minneapolis Heart Inst, Minneapolis, MN USA
[9] Hosp Clin Barcelona, Barcelona, Spain
[10] Laval Univ, CHU Quebec, Intervent Radiol Dept, Quebec City, PQ, Canada
[11] McMaster Univ, Joseph Brant Hosp, Dept Med, Hamilton, ON, Canada
关键词
SYSTEMIC VENOUS-PRESSURE; THORACIC-DUCT; MYOCARDIAL EDEMA; RENAL-FUNCTION; LYMPHANGIOGRAPHY; EMBOLIZATION; ELEVATION; FLOW; INFLAMMATION; CONGESTION;
D O I
10.1016/j.jacc.2021.04.090
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The lymphatic system is an integral part of the circulatory system and plays an important rote in the volume homeostasis of the human body. The complex anatomy and physiology paired with a tack of simple diagnostic toots to study the lymphatic system have led to an underappreciation of the contribution of the lymphatic system to acute and chronic heart failure (HF). Herein, we discuss the physiological rote of the lymphatic system in volume management and the evidence demonstrating the dysregulation of the lymphatic system in HF. Further, we discuss the opportunity to target the lymphatic system in the management of HF and different potential approaches to accessing the lymphatic system. (C) 2021 by the American College of Cardiology Foundation.
引用
收藏
页码:66 / 76
页数:11
相关论文
共 61 条
  • [1] Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000, cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    Adams, KF
    Fonarow, GC
    Emerman, CL
    LeJemtel, TH
    Costanzo, MR
    Abraham, WT
    Berkowitz, RL
    Galvao, M
    Horton, DP
    [J]. AMERICAN HEART JOURNAL, 2005, 149 (02) : 209 - 216
  • [2] Al-Kofahi M., 2017, Clinical and Experimental Neuroimmunology, V8, P199, DOI DOI 10.1111/CEN3.12400
  • [3] The impact of radiation on lymphedema: a review of the literature
    Allam, Omar
    Park, Kitae E.
    Chandler, Ludmila
    Mozaffari, Mohammad Ali
    Ahmad, Maham
    Lu, Xiaona
    Alperovich, Michael
    [J]. GLAND SURGERY, 2020, 9 (02) : 596 - 602
  • [4] EFFECT OF THORACIC-DUCT DRAINAGE ON HYDROSTATIC PULMONARY-EDEMA AND PLEURAL EFFUSION IN SHEEP
    ALLEN, SJ
    DRAKE, RE
    LAINE, GA
    GABEL, JC
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1991, 71 (01) : 314 - 316
  • [5] Superselective retrograde lymphatic duct embolization for management of postoperative lymphatic leak
    Arslan, Bulent
    Masrani, Abdulrahman
    Tasse, Jordan Cameron
    Stenson, Kerstin
    Turba, Ulku Cenk
    [J]. DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY, 2017, 23 (05) : 379 - 380
  • [6] Role of Cardiac Lymphatics in Myocardial Edema and Fibrosis JACC Review Topic of the Week
    Brakenhielm, Ebba
    Gonzalez, Arantxa
    Diez, Javier
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 76 (06) : 735 - 744
  • [7] Lymphatic Vessel Network Structure and Physiology
    Breslin, Jerome W.
    Yang, Ying
    Scallan, Joshua P.
    Sweat, Richard S.
    Adderley, Shaquria P.
    Murfee, Walter L.
    [J]. COMPREHENSIVE PHYSIOLOGY, 2019, 9 (01) : 207 - 299
  • [8] The New Era of the Lymphatic System: No Longer Secondary to the Blood Vascular System
    Choi, Inho
    Lee, Sunju
    Hong, Young-Kwon
    [J]. COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, 2012, 2 (04):
  • [9] THORACIC DUCT-TO-PULMONARY VEIN SHUNT IN TREATMENT OF EXPERIMENTAL RIGHT HEART FAILURE
    COLE, WR
    WITTE, MH
    KASH, SL
    RODGER, M
    BLEISCH, VR
    MUELHEIMS, GH
    [J]. CIRCULATION, 1967, 36 (04) : 539 - +
  • [10] Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities
    Cuijpers, Ilona
    Simmonds, Steven J.
    van Bilsen, Marc
    Czarnowska, Elibieta
    Miqueo, Arantxa Gonzalez
    Heymans, Stephane
    Kuhn, Annika R.
    Mulder, Paul
    Ratajska, Anna
    Jones, Elizabeth A., V
    Brakenhielm, Ebba
    [J]. BASIC RESEARCH IN CARDIOLOGY, 2020, 115 (04)