Chronic hypoxia, physical exercise and PSA: Correlation during high-altitude trekking (2004 K2 expedition)

被引:7
|
作者
Verratti, Vittore
Di Giulio, Camillo
Di Francesco, Simona
Berardinelli, Francesco
Pellicciotta, Mario
Gidaro, Stefano
Zezza, Andrea
Tenaglia, Raffaele
机构
[1] Univ G DAnnunzio, Dipartimento Sci Biomed, Chieti, Italy
[2] Ist Regina Elena, I-00161 Rome, Italy
[3] Univ G DAnnunzio, Urol Clin, Dipartimento Sci Invecchiamento, Chieti, Italy
关键词
hypoxia; chronic; prostate-specific antigen; physical exercise;
D O I
10.1159/000100832
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The aim of the present study was to identify the effects of physical exercise on PSA serum levels and the diagnostic validity of PSA in the screening of prostate cancer in subjects undergoing physical exercise during chronic hypoxia. The study was performed during trekking between 3,200 and 5,600 meters of altitude on K2 mountain for 26 days. Mean serum PSA values before and after exposure did not show significant difference due to physical exercise. These data indicate that physical exercise or mountain hypoxia do not affect the diagnostic validity of PSA. Copyright (c) 2007 S. Karger AG, Basel.
引用
收藏
页码:305 / 307
页数:3
相关论文
共 8 条
  • [1] Marching to the Beet: The effect of dietary nitrate supplementation on high altitude exercise performance and adaptation during a military trekking expedition
    Marshall, Anna R.
    Rimmer, Joanna E.
    Shah, Nishma
    Bye, Kyo
    Kipps, Courtney
    Woods, David R.
    O'Hara, John
    Boos, Christopher J.
    Barlow, Matthew
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2021, 113 : 70 - 77
  • [2] Acclimation to hypoxia increases carbohydrate use during exercise in high-altitude deer mice
    Lau, Daphne S.
    Connaty, Alex D.
    Mahalingam, Sajeni
    Wall, Nastashya
    Cheviron, Zachary A.
    Storz, Jay F.
    Scott, Graham R.
    McClelland, Grant B.
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2017, 312 (03) : R400 - R411
  • [3] BLOOD OXYGEN SATURATION AND HEART RATE DURING EXERCISE A MONTH AFTER A HIGH-ALTITUDE ALPINIST EXPEDITION
    Usaj, Anton
    Burnik, Stojan
    KINESIOLOGY, 2009, 41 (02) : 156 - 163
  • [4] Effects of high-altitude chronic hypoxia on platelet alpha(2)-receptors in man
    Zaccaria, M
    Borea, PA
    Opocher, G
    Ponchia, A
    Varani, K
    Fraccarollo, D
    Scandellari, C
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1997, 27 (04) : 316 - 321
  • [5] Efficacy of Sildenafil on healthy humans in high-altitude hypoxia at rest and during exercise: A meta-analysis
    Dang, Zhan-Cui
    Yang, Zhiquan
    Liu, Shou
    Du, Guo-Mei
    Jin, Linde
    Zhao, Zhong-Zhi
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2024, 27 (02)
  • [6] Cerebral diffusion and T2: MRI predictors of acute mountain sickness during sustained high-altitude hypoxia
    Hunt, John S., Jr.
    Theilmann, Rebecca J.
    Smith, Zachary M.
    Scadeng, Miriam
    Dubowitz, David J.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2013, 33 (03) : 372 - 380
  • [7] Hematologic alterations and CO2 hypersensitivity in male panic disorder patients and normal controls:: Similarities to high-altitude hypoxia and chronic lung disease
    Ross, DC
    Preter, M
    Klein, DF
    DEPRESSION AND ANXIETY, 2001, 14 (02) : 153 - 154
  • [8] Effect of Exposure to Acute and Chronic High-Altitude Hypoxia on the Activity and Expression of CYP1A2, CYP2D6, CYP2C9, CYP2C19 and NAT2 in Rats
    Li, Xiangyang
    Wang, Xuejun
    Li, Yongping
    Yuan, Ming
    Zhu, Junbo
    Su, Xiaodong
    Yao, Xingchen
    Fan, Xueru
    Duan, Yabin
    PHARMACOLOGY, 2014, 93 (1-2) : 76 - 83