A novel visible detection strategy for lysozyme based on gold nanoparticles and conjugated polymer brush

被引:19
|
作者
Gu, Peng [1 ,2 ]
Liu, Xingfen [1 ,2 ]
Tian, Yuanyuan [1 ,2 ]
Zhang, Lei [1 ,2 ]
Huang, Yanqin [1 ,2 ]
Su, Shao [1 ,2 ]
Feng, Xiaomiao [1 ,2 ]
Fan, Quli [1 ,2 ]
Huang, Wei [3 ,4 ]
机构
[1] Nanjing Univ Posts & Telecommun, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Key Lab Organ Elect & Informat Displays, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Univ Posts & Telecommun, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Inst Adv Mat, Nanjing 210023, Jiangsu, Peoples R China
[3] Nanjing Tech Univ Nanjing Tech, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Key Lab Flexible Elect, Nanjing 211816, Jiangsu, Peoples R China
[4] Nanjing Tech Univ Nanjing Tech, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Inst Adv Mat, Nanjing 211816, Jiangsu, Peoples R China
来源
SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 246卷
关键词
Biosensor; Conjugated polymer; Gold nanoparticle; Lysozyme; HIGH CHARGE-DENSITY; IN-VITRO SELECTION; COLORIMETRIC DETECTION; ENERGY-TRANSFER; QUANTUM DOTS; POLYELECTROLYTE BRUSH; DNA; APTAMER; EFFICIENT; DISEASE;
D O I
10.1016/j.snb.2017.01.043
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We developed a new strategy by combining gold nanoparticles (AuNPs) with a fluorescent conjugated polymer brush (ThNI) for colorimetric and fluorometric detection of human lysozyme. This strategy was successfully applied to assay lysozyme in buffer and human saliva. In comparison with previous reported methods, our approach has the advantages of simpleness, sensitivity, label-free property, and low cost. (C) 2017 Published by Elsevier B.V.
引用
收藏
页码:78 / 84
页数:7
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