Selective Imaging of Lipids in Adipocytes by Using an Imidazolyl Derivative of Perylene Bisimide

被引：2
作者：
Mishra, Ruchika [1 ]
Mushtaq, Zeeshan [2 ]
Regar, Ramprasad [1 ]
Mallik, Bhagaban [2 ]
Kumar, Vimlesh [2 ]
Sankar, Jeyaraman [1 ]
机构：
[1] Indian Inst Sci Educ & Res Bhopal, Dept Chem, Bhopal Bypass Rd, Bhopal 462066, India
[2] Indian Inst Sci Educ & Res Bhopal, Dept Biol Sci, Bhopal Bypass Rd, Bhopal 462066, India
来源：
CHEMBIOCHEM | 2018年 / 19卷 / 13期
关键词：
biomarkers; dyes; pigments; fluorescent probes; imaging agents; lipids; PHOTOPHYSICAL PROPERTIES; DROSOPHILA-MELANOGASTER; OPTICAL-PROPERTIES; FLUORESCENT; DYES; METABOLISM; DROPLETS; TRACKING; FAT; NANOPARTICLES;
D O I：
10.1002/cbic.201800134
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A small molecule, perylene bisimide imidazolyl derivative (PBI-ID), has been identified and developed as a specific marker for labelling multifunctional fat bodies in various organisms, including Drosophila and mammalian adipocytes. Interestingly, PBI-ID neither labels the plasma membranes nor cell nuclei by trapping into it. A remarkable feature of unbound PBI-ID is diminished fluorescence, which reduces the background emission noise, while contrasting the bound state effectively.
引用
收藏
页码：1386 / 1390
页数：5
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