Vasomotor symptoms in menopause: a biomarker of cardiovascular disease risk and other chronic diseases?

被引：73

作者：

Biglia, N. ^{[1
]}

Cagnacci, A. ^{[2
]}

Gambacciani, M. ^{[3
]}

Lello, S. ^{[4
]}

Maffei, S. ^{[5
]}

Nappi, R. E. ^{[6
]}

机构：

[1] Univ Turin, Dept Obstet & Gynecol, Osped Mauriziano Umberto I, Sch Med, Turin, Italy

[2] Azienda Policlin Modena, Dept Obstet Gynecol & Pediat, Gynecol & Obstet Unit, Modena, Italy

[3] Pisa Univ Hosp, Dept Obstet & Gynecol, Pisa, Italy

[4] Policlin Gemelli Fdn, Dept Woman & Child Hlth, Rome, Italy

[5] Italian Natl Res Council, Cardiovasc Endocrinol & Metab Dept, Cardiovasc Gynecol Endocrinol Unit, Reg Toscana G Monasterio Fdn, Pisa, Italy

[6] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, IRCCS S Matteo Fdn, Res Ctr Reprod Med Gynecol Endocrinol & Menopause, Pavia, Italy

来源：

CLIMACTERIC | 2017年 / 20卷 / 04期

关键词：

Menopause; hot flushes; cardiovascular disease; vasomotor symptoms; biomarker; chronic disease; CORONARY-HEART-DISEASE; BONE-MINERAL DENSITY; HOT FLASHES; WOMENS HEALTH; COGNITIVE PERFORMANCE; CLIMACTERIC SYMPTOMS; MEMORY PERFORMANCE; MIDLIFE WOMEN; ESTROGENS; ASSOCIATION;

D O I：

10.1080/13697137.2017.1315089

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Menopausal disorders may include shorter-term symptoms, such as hot flushes and night sweats (vasomotor symptoms, VMS) and longer-term chronic conditions such as cardiovascular disease (CVD), osteoporosis, and cognitive impairment. Initially, no clear link between the shorter-term symptoms and longer-term chronic conditions was evident and these disorders seemed to occur independently from each other. However, there is a growing body of evidence demonstrating that VMS may be a biomarker for chronic disease. In this review, the association between VMS and a range of chronic postmenopausal conditions including CVD, osteoporosis, and cognitive decline is discussed. Prevention of CVD in women, as for men, should be started early, and effective management of chronic disease in postmenopausal women has to start with the awareness that VMS during menopause are harbingers of things to come and should be treated accordingly.

引用

页码：306 / 312

页数：7

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