Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions

被引：143

作者：

Al-Abri, Seif S. ^{[1
]}

Al Abaidani, Idris ^{[2
]}

Fazlalipour, Mehdi ^{[3
]}

Mostafavi, Ehsan ^{[4
]}

Leblebicioglu, Hakan ^{[5
]}

Pshenichnaya, Natalia ^{[6
]}

Memish, Ziad A. ^{[7
]}

Hewson, Roger ^{[8
]}

Petersen, Eskild ^{[9
]}

Mala, Peter ^{[10
]}

Tran Minh Nhu Nguyen ^{[10
]}

Malik, Mamunur Rahman ^{[10
]}

Formenty, Pierre ^{[11
]}

Jeffries, Rosanna ^{[11
]}

机构：

[1] Minist Hlth, Muscat, Oman

[2] Minist Hlth, Dept Communicable Dis, Muscat, Oman

[3] Pasteur Inst Iran, Dept Arbovirus & Viral Hemorrhag Fever, Tehran, Iran

[4] Pasteur Inst Iran, Res Ctr Emerging & Reemerging Infect Dis, Tehran, Iran

[5] Ondokuz Mayis Univ, Dept Infect Dis & Clin Microbiol, Samsun, Turkey

[6] Rostov State Med Univ, Dept Infect Dis, Moscow, Russia

[7] Emory Univ, Sch Publ Hlth, Hubert Dept Global Hlth, Atlanta, GA USA

[8] Natl Infect Serv Publ Hlth England, Arboviruses & VHFs, WHO Collaborating Ctr Special Pathogens, Salisbury, Wilts, England

[9] Royal Hosp, Infect Dis, Muscat, Oman

[10] WHO, Infect Hazards Management, Eastern Mediterranean Reg Off, Cairo, Egypt

[11] WHO, Infect Hazards Management, Geneva, Switzerland

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2017年 / 58卷

关键词：

CCHF; Eastern Mediterranean Region; Ixodid ticks; CCHF virus; Knowledge gaps; VIRUS-INFECTION; RIBAVIRIN; OUTBREAK; CCHF; TRANSMISSION; AFGHANISTAN; EFFICACY; EPIDEMIOLOGY; SURVEILLANCE; PAKISTAN;

D O I：

10.1016/j.ijid.2017.02.018

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Crimean-Congo haemorrhagic fever (CCHF) is the most widespread, tick-borne viral disease affecting humans. The disease is endemic in many regions, such as Africa, Asia, Eastern and Southern Europe, and Central Asia. Recently, the incidence of CCHF has increased rapidly in the countries of the World Health Organization Eastern Mediterranean Region (WHO EMR), with sporadic human cases and outbreaks of CCHF being reported from a number of countries in the region. Despite the rapidly growing incidence of the disease, there are currently no accurate data on the burden of the disease in the region due to the different surveillance systems used for CCHF in these countries. In an effort to increase our understanding of the epidemiology and risk factors for the transmission of the CCHF virus (CCHFV; a Nairovirus of the family Bunyaviridae) in the WHO EMR, and to identify the current knowledge gaps that are hindering effective control interventions, a sub-regional meeting was organized in Muscat, Oman, from December 7 to 9, 2015. This article summarizes the current knowledge of the disease in the region, identifies the knowledge gaps that present challenges for the prevention and control of CCHFV, and details a strategic framework for research and development activities that would be necessary to curb the ongoing and new threats posed by CCHFV. (C) 2017 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

引用

页码：82 / 89

页数：8

共 77 条

[1] A seroepidemiological survey of Crimean Congo hemorrhagic fever among Cattle in North Kordufan State, Sudan [J].