Towards the total synthesis of amphidinolide E: an enantioselective synthesis of C12-C29 fragment

被引：20

作者：

Gurjar, MK ^{[1
]}

Mohapatra, S ^{[1
]}

Phalgune, UD ^{[1
]}

Puranik, VG ^{[1
]}

Mohapatra, DK ^{[1
]}

机构：

[1] Natl Chem Lab, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 42期

关键词：

mercuriocyclization; Stille coupling; Wittig reaction; hydroboration-oxidation;

D O I：

10.1016/j.tetlet.2004.08.143

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioselective synthesis of the C12-C29 fragment of amphidinolide E is described. Key transformations include an intramolecular mercuriocyclization reaction, stereoselective introduction of methyl group at the C2 position, and Stille coupling for the introduction of the diene side chain. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：7899 / 7902

页数：4

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