High-resolution reference ranges for estradiol, luteinizing hormone, and follicle-stimulating hormone in men and women using the AxSYM assay system

Objectives: High-resolution reference ranges are essential for reproductive hormones due to the significant day-to-day variation seen with these analytes. Design and methods: The performance of AxSYM assays for estradiol, luteinizing hormone (LH), and follicle-stimulating homone was evaluated. Results: These studies validate the performance of each assay, permitting high-resolution reference ranges to be established. Conclusions: The high-resolution reference range data provided herein for both normally cycling females and males should be applicable to a wide variety of clinical situations. (C) 2004 The Canadian Society of Clinical Chemists. All rights reserved.