Calcium-alginate beads loaded with gallic acid: Preparation and characterization

被引：93

作者：

Li, Jinglei ^{[1
]}

Kim, Su Yeon ^{[1
]}

Chen, Xiguang ^{[2
]}

Park, Hyun Jin ^{[1
]}

机构：

[1] Korea Univ, Sch Life Sci & Biotechnol, 5 Ka, Seoul 136701, South Korea

[2] Ocean Univ China, Coll Marine Life Sci, Qingdao 266003, Shandong, Peoples R China

来源：

LWT-FOOD SCIENCE AND TECHNOLOGY | 2016年 / 68卷

基金：

新加坡国家研究基金会;

关键词：

Electrospray; Voltage; Cross-linking; Size; In vitro release; BRAIN TARGETED DELIVERY; BETA-CYCLODEXTRIN; NANOPARTICLES; ANTIOXIDANT; CURCUMIN; RELEASE; SPRAY; MICROENCAPSULATION; MICROPARTICLES; ENCAPSULATION;

D O I：

10.1016/j.lwt.2016.01.012

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Electrospray technique was used to prepare alginate beads with controllable size from about 200 gm to 1.3 mm by adjusting the working voltage. The encapsulation ability of alginate beads for gallic acid, a model hydrophilic phenolic compound, was investigated. Loading amount of gallic acid varied from 7 g/100 g-12 g/100 g among alginate beads samples. Fourier-transform infrared and differential scanning calorimetry result confirmed the inclusion of gallic acid. Moreover, no autoxidation of gallic acid was observed in the formulated alginate beads. Release profile result indicated that in simulated intestinal fluid the release was faster than that in gastric fluid. The release pattern was influenced by both loading amount of gallic acid and size of alginate beads. Our results suggest that alginate beads fabricated by electrospray method is a promising delivery system for water soluble phenolic compound like gallic acid. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：667 / 673

页数：7

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