Surface-polymerized biomimetic nanofibrils for the cell-directed association of 3-D scaffolds

被引:18
作者
Kim, Hye Sung [1 ]
Yoo, Hyuk Sang [1 ,2 ]
机构
[1] Kangwon Natl Univ, Coll Biomed Sci, Dept Biomed Mat Engn, Chunchon 200701, South Korea
[2] Kangwon Natl Univ, Inst Biosci & Biotechnol, Chunchon 200701, South Korea
基金
新加坡国家研究基金会;
关键词
ADHESION; ENCAPSULATION; HYDROGELS; CARTILAGE; ALGINATE;
D O I
10.1039/c4cc06875k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
For the cell-directed association of nanofibrils, polymeric nanofibrils (NFs) were fabricated by fragmentation of electrospun nanofibers and subsequent surface-decoration with poly(methacrylate) derivatives via ATRP. The decorated NFs showed higher degrees of protein sequestration and enhanced cell proliferation with free infiltration of cells, which leads to hydrogel-like behavior.
引用
收藏
页码:306 / 309
页数:4
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