Synthesis and Biological activity of 4-(4,6-Disubstituted-pyrimidin-2-yloxy)phenoxy Acetates

被引：8

作者：

Jiang, Lin ^{[1
]}

Wang, Hao ^{[1
]}

Wang, Maorong ^{[1
]}

Teng, Xinhuan ^{[2
]}

机构：

[1] Shandong Agr Univ, Coll Chem & Mat Sci, Tai An 271018, Shandong, Peoples R China

[2] Shandong Agr Univ, Coll Plant Protect, Tai An 271018, Shandong, Peoples R China

来源：

MOLECULES | 2010年 / 15卷 / 02期

关键词：

pyrimidine; phenoxyacetate; synthesis; herbicidal activity; COENZYME-A CARBOXYLASE; HERBICIDAL ACTIVITY; DESIGN;

D O I：

10.3390/molecules15021074

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ten novel 4-(4,6-dimethoxypyrimidin-2-yloxy)phenoxy acetates and 4-(4,6-dimethylpyrimidin-2-yloxy)phenoxy acetates were synthesized with hydroquinone, 2-methylsulfonyl-4,6-disubstituted-pyrimidine and chloroacetic ester as starting materials. The products were characterized by IR, H-1-NMR, MS spectra and elemental analyses. Preliminary bioassay indicates that the target compounds possess high herbicidal activity against monocotyledonous plants such as Digitaria sanguinalis L. at concentrations of 100 mg/L and 50 mg/L.

引用

页码：1074 / 1081

页数：8

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