A replication study on P300 single trial analysis in schizophrenia:: confirmation of a reduced number of 'true positive' P300 waves

被引：10

作者：

Wagner, P ^{[1
]}

Röschke, J ^{[1
]}

Grözinger, M ^{[1
]}

Mann, K ^{[1
]}

机构：

[1] Univ Mainz, Dept Psychiat, D-6500 Mainz, Germany

来源：

JOURNAL OF PSYCHIATRIC RESEARCH | 2000年 / 34卷 / 03期

关键词：

P300; schizophrenia; single trial analysis; auditory event-related potentials; information processing;

D O I：

10.1016/S0022-3956(00)00010-8

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

A single trial analysis of event-related potentials (auditory odd-ball paradigm) of 20 schizophrenics was performed in comparison to matched healthy controls. The purpose of the study was to test the hypothesis that in schizophrenia the well-known P300 amplitude reduction of averaged event-related potentials is due to fewer elicited single trial P300 waves. The results of the present study support this finding of our previous exploratory investigation and point to the view that schizophrenics reveal basal disturbances in information processing due to inadequately elicited electrophysiological responses to target stimuli. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：255 / 259

页数：5

共 21 条

[1] MAXIMUM VARIANCE OF LATE COMPONENT EVENT-RELATED POTENTIALS (190-240 MS) IN UNMEDICATED SCHIZOPHRENIC-PATIENTS [J].