A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions

被引：244

作者：

Lundgren, Rylan J. ^{[1
]}

Peters, Brendan D. ^{[1
]}

Alsabeh, Pamela G. ^{[1
]}

Stradiotto, Mark ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4J3, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 24期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ammonia; arylation; homogeneous catalysis; palladium; N; P ligands; AQUEOUS AMMONIA; C-N; AMINATION; HALIDES; AMINES; DIARYLAMINES; SULFONATES; ANILINES; BROMIDES; LIGANDS;

D O I：

10.1002/anie.201000526

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Amazing ammonia: A new air-stable P,N-ligand (Mor-DalPhos) is reported that enables the palladium-catalyzed crosscoupling of ammonia to a variety of aryl chloride and aryl tosylate substrates with high chemoselectivity and, for the first time, at room temperature (see scheme; Ad = adamantyl, Ts=para-toluenesulfonyl). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA,.

引用

页码：4071 / 4074

页数：4

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