A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions

被引：238
作者：
Lundgren, Rylan J. [1 ]
Peters, Brendan D. [1 ]
Alsabeh, Pamela G. [1 ]
Stradiotto, Mark [1 ]
机构：
[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4J3, Canada
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 24期
基金：
加拿大自然科学与工程研究理事会;
关键词：
ammonia; arylation; homogeneous catalysis; palladium; N; P ligands; AQUEOUS AMMONIA; C-N; AMINATION; HALIDES; AMINES; DIARYLAMINES; SULFONATES; ANILINES; BROMIDES; LIGANDS;
D O I：
10.1002/anie.201000526
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Amazing ammonia: A new air-stable P,N-ligand (Mor-DalPhos) is reported that enables the palladium-catalyzed crosscoupling of ammonia to a variety of aryl chloride and aryl tosylate substrates with high chemoselectivity and, for the first time, at room temperature (see scheme; Ad = adamantyl, Ts=para-toluenesulfonyl). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA,.
引用
收藏
页码：4071 / 4074
页数：4
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