Direct Access to Isolated Biomolecules under Ambient Conditions

被引：37

作者：

Chingin, Konstantin ^{[1
]}

Frankevich, Vladimir ^{[1
]}

Balabin, Roman M. ^{[1
]}

Barylyuk, Konstantin ^{[1
]}

Chen, Huanwen ^{[2
]}

Wang, Rui ^{[1
]}

Zenobi, Renato ^{[1
]}

机构：

[1] ETH, Dept Chem & Appl Biosci, CH-8093 Zurich, Switzerland

[2] E China Inst Technol, Dept Appl Chem, Fuzhou 344000, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 13期

关键词：

biomolecules; electrospray ionization gas phase laser spectroscopy; mass spectrometry; IONIZATION-MASS-SPECTROMETRY; ELECTROSONIC SPRAY IONIZATION; ATMOSPHERIC-PRESSURE; GAS-PHASE; PROTEIN COMPLEXES; IONS; DISSOCIATION; PEPTIDES; SURFACES; FLUORESCENCE;

D O I：

10.1002/anie.200906213

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the transfer of nonvolatiles into the gas phase, thermal evaporation is extremely inefficient because of the rapid chemical degradation (left). Generally, nonvolatiles can be brought into the gas phase by softionization methods such as ESI or MALDI for investigation by MS (right). Now a method has been developed to access isolated biomolecules in the gas phase under ambient conditions (center). (Figure Presented). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2358 / 2361

页数：4

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