Salvage Method for Unplanned Excision of Soft Tissue Sarcoma: Long-term Results of Second-look Surgery Following Radio-hyperthermo-chemotherapy

被引：0

作者：

Hayashi, Katsuhiro ^{[1
,2
]}

Yamada, Satoshi ^{[1
]}

Inatani, Hiroyuki ^{[1
,2
]}

Okamoto, Hideki ^{[1
]}

Takeuchi, Akihiko ^{[2
]}

Nishida, Hideji ^{[2
]}

Yamamoto, Norio ^{[2
]}

Tsuchiya, Hiroyuki ^{[2
]}

Otsuka, Takanobu ^{[1
]}

机构：

[1] Nagoya City Univ, Sch Med, Dept Orthopaed Surg, Nagoya, Aichi 467, Japan

[2] Kanazawa Univ, Grad Sch Med Sci, Dept Orthopaed Surg, Kanazawa, Ishikawa 9208641, Japan

来源：

ANTICANCER RESEARCH | 2015年 / 35卷 / 01期

关键词：

Soft tissue sarcoma; hyperthermotherapy; unplanned excision; chemotherapy; surgery; PREOPERATIVE CHEMOTHERAPY; APOPTOSIS; CELLS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We have established a "second-look operation" protocol that consists of whole biopsy of surgical scar tissue following radio-hyperthermo-chemotherapy (RHC) after unplanned excision of soft tissue sarcoma. Out of 30 patients who underwent RHC for soft tissue sarcoma at our Institution, 6 were enrolled into this study to undergo a second-look operation for unplanned excision. Radiotherapy was given to a total dose of 32 Gy. Hyperthermia was conducted once a week, for a total of five sessions. Chemotherapy was performed at weekly intervals. Surgery was performed to excise the scar tissue that was enhanced on preoperative MRI. In all six cases, no residual tumors were identified in resected scar tissue; thus, no additional wide excision was performed. The average follow-up period was 10.9 years. There were no local recurrences, and all patients were alive at their final follow-up. Long-term follow-up confirmed that RHC can replace additional wide excision for unplanned excision of soft tissue sarcoma.

引用

页码：493 / 498

页数：6

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