Epidemiological, clinical and morphological aspects of kidney damage in COVID-19

被引：2

作者：

Daminov, Batir ^{[1
]}

Abdullaev, Sherzod ^{[1
]}

Sharapov, Olimkhon ^{[1
]}

Igamberdieva, Ranokhon ^{[1
]}

机构：

[1] Tashkent Pediat Med Inst, Tashkent, Uzbekistan

来源：

JOURNAL OF RENAL INJURY PREVENTION | 2021年 / 10卷 / 03期

关键词：

SARS-CoV-2; COVID-19; Pandemic; Kidney disease; Coronavirus infection; Chronic kidney disease; Acute renal failure;

D O I：

10.34172/jrip.2021.17

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The mini-review presents modern data on the epidemiology, clinical and morphological aspects of kidney damage in COVID-19. Potential mechanisms of kidney involvement in the clinical picture of the disease may include cytokine damage, cross-organ damage, and systemic effects that determine the treatment strategy. These mechanisms are closely interrelated and are especially important for individuals undergoing extracorporeal therapy and kidney transplants. Autopsy data provide evidence of SARS-CoV-2 virus invasion into kidney tissue with damage to tubular epithelial cells and podocytes, and erythrocyte aggregation in persons with severe COVID-19. By including people with chronic kidney disease in planned COVID-19 research protocols, an evidence base for effective and safe treatments can be generated.

引用

页码：1 / 5

页数：5

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